Project Grant K23AG093089
- The National Institute on Aging awarded the University of Florida $439,739 on June 1, 2026, under the Aging Research program (CFDA 93.866) to investigate biobehavioral signatures of repetitive head impacts at the intersection of aging and Alzheimer's disease. The award funds a longitudinal multi-site study examining fluid biomarkers, neuroimaging, and cognition in aging adults with and without prior repetitive head impacts (RHI). The research addresses how RHI—exposure from contact sports,...
- The National Institute on Aging awarded the University of Florida $5.551 million on July 1, 2026, under the Aging Research program (CFDA 93.866) to identify neural signatures that distinguish early Alzheimer's disease from normal aging. The recipient will record electrical activity from ten brain regions across the lifespan in human tauopathy mouse models (HTAU mice) and wild-type controls (C57BL/6J), computing new electrical oscillatory features called electome factors to distinguish between...
- The National Institute on Aging awarded the University of Florida $447,444 on September 9, 2025, under the Aging Research program (CFDA 93.866) to support a five-year leadership development program in real-world data analytics focused on sleep and Alzheimer's disease prevention. The recipient will design and execute comprehensive leadership training to transition into a multiple R01-funded researcher with established expertise in using real-world data to advance sleep health and Alzheimer's...
- The National Institute on Aging awarded the University of Florida $788,481 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop clinical diagnostic tools for chronic traumatic encephalopathy (CTE) during life, distinguishing CTE from Alzheimer's disease and related dementias. The research will apply automated imaging differentiation of dementia (AIDD), a novel disease classification method, to brain imaging data. Blood-based biomarkers (NulisaSeq) will complement...
- The National Institute on Aging awarded the University of Miami $145,706 on July 1, 2026, under the Aging Research program (CFDA 93.866) to support a Mentored Patient-Oriented Research Career Development (K23) award for research on gray matter microstructure as a sleep-related marker of preclinical Alzheimer's disease. The award funds research and structured career-development training for a clinical sleep neurologist to develop into an independent clinical scientist. The research leverages...
- The National Institute on Aging awarded the University of Florida $182,570 on July 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a prospective cohort study validating diffuse optical tomography (DOT) as a portable neuroimaging biomarker for mapping brain function in delirium and post-delirium Alzheimer's disease and related dementias. The award supports research examining whether DOT can identify impaired cerebral oxygenation and functional dysconnectivity in the...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $198,352 to the University of Georgia Research Foundation, Inc. on March 15, 2026, under the Aging Research program (CFDA 93.866) to support research on molecular determinants of age-related cognitive decline in the basal forebrain to lateral entorhinal cortex circuit. The research identifies molecular signatures of vulnerability in the basal forebrain cholinergic neuron (BFCN) to lateral entorhinal...
- The National Institute on Aging awarded the University of Virginia $583,815 on August 15, 2026, under the Aging Research program (CFDA 93.866) to support research into oligodendrocyte lineage dysfunction during aging and Alzheimer's disease. The project aims to understand how myelin loss—a pathology common to both aging and Alzheimer's disease—develops in the central nervous system and to identify therapeutic targets for cognitive impairment. The research focuses on oligodendrocyte precursor...
- The National Institute on Aging awarded the University of South Florida $3,331,541 on September 22, 2025, under the Aging Research program (CFDA 93.866) to conduct transcriptome-wide mapping of brain N6-methyladenosine (m6A) methylome in Alzheimer's disease. The award runs through May 31, 2030, with place of performance in Tampa, Florida. The research will create the first high-resolution reference map of brain m6A methylome in older adults using novel base-resolution quantitative m6A...
- The National Institute on Aging awarded New York University $6.203 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to examine peripheral immune markers and vascular dysfunction as contributors to cognitive decline and Alzheimer's disease. The research integrates circulating biomarkers—platelet aggregation, neutrophil activity, and proteomic data—with advanced imaging to assess associations between vascular and immune dysfunction and cerebrovascular burden, amyloid...
The National Institute on Aging awarded $191,832 to North Florida Foundation For Research And Education, Inc. on August 15, 2026, under the Aging Research program (CFDA 93.866) to support a K23 career development grant focused on brain aging and Alzheimer's disease risk. The award funds research investigating the relationship between cognition and the autonomic regulatory system in older adults at varying risk for Alzheimer's disease and related dementias. The principal investigator will characterize neural functioning of predictive coding networks, autonomic flexibility in response to cognitive load, and multi-system stress burden biomarkers using multimodal neuroimaging and blood-based biomarkers. The research builds on preliminary data from work with older adults recovering from mild traumatic brain injury showing associations between memory, autonomic functions, and predictive coding networks. The award also supports the principal investigator's development as an independent investigator in clinical science and translational research through a structured training plan addressing expertise in clinical research with complex multimodal data, time-series analyses, fluid biomarkers, and mentorship to transition to independent research management. Performance is based in Gainesville, Florida, with a period of performance from August 15, 2026, through May 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $191.8k | 8/14/26 |