Project Grant K23AG090622
- Federal Grant Award Summary The University of Florida Division of Sponsored Research received a $2.78 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective July 1, 2026, through June 30, 2030. This award supports research directed toward identifying early neural signatures of prodromal Alzheimer's disease (AD) that can distinguish between early cognitive decline and normal aging. The project delivers two primary research...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of Florida a Project Grant totaling $298,296 on September 9, 2025, under the Aging Research program (CFDA 93.866) to support a five-year leadership development initiative extending through May 31, 2030. The award funds a comprehensive training program designed to advance the principal investigator's transition from early-career researcher to a multi-R01-funded investigator with established expertise in...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $126,640 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective September 1, 2025, through May 31, 2030. This research initiative applies machine learning approaches to develop a robust, standardized measure of allostatic load (AL)—a physiological indicator of cumulative "wear and tear" that serves as a pre-clinical marker for chronic...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $507,214 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 15, 2026, with a completion date of January 31, 2028. This exploratory/developmental R21 grant supports systematic investigation of long-noncoding RNA SLAMR (SLAMR lncRNA) and its role in Alzheimer's disease pathogenesis. The research aims to elucidate how SLAMR...
- Federal Project Grant Award Summary The National Institute on Aging awarded a Project Grant of $439,739 to the University of Florida Division of Sponsored Research, effective June 1, 2026 through May 31, 2028, under the Aging Research program (CFDA 93.866). This R01 award from an Early-Stage Investigator funds a longitudinal research study examining the biobehavioral signatures of repetitive head impacts (RHI) at the intersection of aging and Alzheimer's disease. The research will investigate...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $730,938 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective July 1, 2026 through May 31, 2031. The award funds research to develop and refine combinatorial rehabilitation treatments for individuals with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by motor neuron loss, paralysis, and respiratory...
- Federal Grant Award Summary The National Institute on Aging awarded a K23 (Mentored Patient-Oriented Research Career Development) grant of $145,706 to the University of Miami's Office of Research Administration—School of Medicine on July 1, 2026, under the Aging Research program (CFDA 93.866). This award supports both research and structured career development training for a clinical sleep neurologist through April 30, 2031. The grant delivers a comprehensive training framework consisting of...
- Federal Grant Award Summary The National Institute on Aging awarded a $618,410 Project Grant to The Johns Hopkins University effective February 1, 2026, through January 31, 2029, under the Aging Research program (CFDA 93.866). The project will develop a deep learning-based miniature microscope designed to enable early detection of Alzheimer's disease (AD) through imaging of presymptomatic pathology. The research addresses critical gaps in current AD diagnostics by investigating how amyloid and...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $2.33 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2029. The award funds research evaluating neuroimmune mechanisms and therapeutic targeting potential of the luteinizing hormone/chorionic gonadotropin (LH/CG) receptor in menopausal and Alzheimer's disease-affected brains....
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of South Florida $3.297 million under the Aging Research program (CFDA 93.866) for a four-year project period (September 1, 2025 – August 31, 2029) to develop novel peptidomimetic biomaterials that inhibit amyloid-beta (Aβ42) aggregation in Alzheimer's disease. The research deliverables include the rational design and characterization of structurally related analogues to a lead compound that stabilizes Aβ...
The University of Florida Division of Sponsored Research received a $182,570 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective July 1, 2026, through April 30, 2031. This K23 career development award supports a prospective cohort study investigating Diffuse Optical Tomography (DOT) as a portable neuroimaging biomarker for mapping brain function changes associated with delirium and subsequent cognitive decline in critically ill older adults. The research addresses a significant clinical gap: more than 75% of critically ill older adults develop delirium, and approximately 50% of intensive care unit (ICU) survivors subsequently suffer from mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (ADRD). The project leverages optical imaging technology to overcome logistical and technical limitations of conventional neuroimaging modalities by enabling bedside assessment of cerebral hemodynamics and functional connectivity. The deliverables include longitudinal neuroimaging data characterizing differences in DOT-measured cerebral oxygenation and functional dysconnectivity during acute delirium, post-delirium resolution, and long-term cognitive outcomes. This research is expected to establish DOT as a validated biomarker for identifying early neurobiological changes linking ICU delirium to long-term cognitive decline, potentially advancing clinical understanding of shared pathways underlying these conditions and informing future intervention strategies for high-risk older adult populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $182.6k | 6/30/26 |