Project Grant K08NS144606
- Grant Award Summary The University of Pennsylvania received a $232,605 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective July 1, 2026 through June 30, 2031. This award supports research investigating microglial-derived extracellular vesicles (MDEVs) as biomarkers for traumatic brain injury (TBI). The research utilizes a novel microfluidic...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $224,265 to the University of Pittsburgh under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025, through July 31, 2030. This Career Development Award supports the development and refinement of novel interventions to improve neurological prognostication for patients with hypoxic-ischemic brain injury...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $126,735 to the Icahn School of Medicine at Mount Sinai on February 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This K99/R00 career development award supports Dr. Amelia Hicks in establishing her independent research career focused on post-traumatic neurodegeneration (PTND)—the intersection of traumatic brain injury...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a K08 Mentored Research Career Development Award of $221,400 to The Children's Hospital of Philadelphia (CHOP) effective May 15, 2026, through March 31, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award supports a structured training program designed to develop an independent investigator with expertise in...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $215,350 to the University of Pennsylvania on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This Project Grant supports a research and mentored career development initiative focused on investigating metabolic reprogramming in myeloid-derived suppressor cells (MDSCs) within glioblastoma tumors. The award...
- Federal Project Grant Award Summary The University of Pennsylvania received a $231,325 Project Grant awarded July 10, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a five-year research initiative (through June 30, 2030) investigating the neurophysiologic signatures of essential tremor and the mechanisms by which deep brain stimulation...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The University of Pennsylvania a Project Grant totaling $2,817,215 on August 7, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The four-year award, scheduled for completion by July 31, 2029, funds research to elucidate the role of TRIM10 protein in maintaining TDP-43 (TAR DNA-binding protein 43) solubility and...
- Federal Project Grant Award Summary Brown University received a $254,400 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded May 1, 2026, with completion targeted for April 30, 2028. The research focuses on developing and evaluating D-SYN3, a novel macrocyclic therapeutic compound that enhances brain-derived neurotrophic factor (BDNF)...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $654,218 Project Grant to the University of Maryland, Baltimore on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The five-year research initiative, scheduled for completion on July 31, 2030, investigates the mechanisms and intervention strategies of cyclic GMP-AMP synthase (cGAS) signaling in brain trauma-induced...
- Federal Grant Award Summary This $230,925 Project Grant, awarded August 1, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), supports a five-year research initiative at Yale University examining central nervous system inflammation in aneurysmal subarachnoid hemorrhage (ASAH) patients. The project investigates whether the duration of the pro-inflammatory phase...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Career Development Award of $233,847 to the University of Pennsylvania, with performance occurring in Philadelphia, PA. The award, issued June 1, 2026, with completion targeted for March 31, 2031, supports Dr. Samuel Shin's development as an independent scientist specializing in iron-associated mitochondrial injury in traumatic brain injury (TBI). The grant funds acquisition of technical expertise in flow cytometry, transgenic techniques using adeno-associated virus vectors, and immunohistochemistry to study secondary brain injury mechanisms and iron metabolism changes following TBI. This career development initiative is administered under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award delivers comprehensive career support including formal didactic training in mitochondrial biology, redox physiology, biostatistics, ethics, and grant writing. Dr. Shin's development is overseen by a mentoring team led by Dr. Todd Kilbaugh and Dr. Frances Jensen from the University of Pennsylvania and Children's Hospital of Philadelphia, supplemented by four specialized advisors including Dr. Douglas Wallace (mitochondrial physiology), Dr. Rajiv Ratan (ferroptosis and iron metabolism), and other recognized experts in TBI therapeutics and biostatistics. The structured mentorship and training program positions the investigator to establish himself as a recognized expert in mitochondrial and iron-associated oxidative stress mechanisms in TBI research.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $233.8k | 5/20/26 |