Project Grant K08HL171943
Award Date 8/15/25
Completion Date 7/31/30
Dollars Obligated $169K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Pennsylvania, USA
Similar Awards
- This $153,117 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of the recipient's independent research career as an academic hematopathology physician-scientist. The key objectives are to study hematopoietic stem and progenitor cell (HSPC) crosstalk and transplantation, with the overarching goal of improving HSPC transplantation outcomes. The award period runs from August 1, 2025 to July 31,...
- This $240,552 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports a research project titled "Unraveling the Cell Networks in Bone Marrow Through Transcriptomic and Epigenetic Profiling" at the University of Pennsylvania. The project aims to generate a comprehensive single-cell transcriptomic and regulomic map of human bone marrow cells and experimentally establish the mesenchymal cell hierarchy in human bone....
- This federal Project Grant award for $802,301, provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports research by Weill Medical College of Cornell University to investigate the mechanisms that control the bone marrow "niche" environment and its role in expanding mutated blood stem cells that increase the risk of cardiovascular disease and cancer. The research aims to identify signaling pathways that can be targeted to prevent...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $1,123,357.00 to support research on the bone marrow microenvironment and its role in regulating blood cell production. The research, to be conducted by the Children's Hospital Medical Center in Cincinnati, Ohio, aims to define the spatial organization and specialized vascular microenvironments within the bone marrow that recruit and...
- This federal Project Grant award of $248,955 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research by Howard University to characterize the roles of bivalent chromatin domains in regulating CD4+ T cell differentiation and plasticity. The award will enable the principal investigator to expand their biological skills and apply a novel single-cell epigenetic profiling technique (iSCCHIC-seq) to study how bivalent domains regulate...
- This federal Project Grant award of $165,366 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate the role of transcription factors KLF2 and KLF4 in cardiac fibroblast function and their relationship to heart failure. The award was granted to Drexel University, a private research university in Pennsylvania, to conduct this research from September 1, 2025 through August 31, 2030. The project aims to advance the...
- The federal Project Grant award of $108,512 was provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The award will fund research to determine how inflammation is regulated in Runx1-Familial Platelet Disorder (Runx1-FPD), a genetic disorder that increases the risk of hematologic malignancies. The research aims to...
- This Project Grant award of $125,532.00, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to investigate the disruption of the clonal architecture of human hematopoietic stem cells driven by high-effect somatic and germline genetic variants, and identify the resulting phenotypic changes that lead to impaired stem cell function and increased disease risk with aging. The research will utilize a mitochondrial lineage tracing...
- This Project Grant award, provided by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), supports research on the use of donor-derived cell-free DNA for risk stratification and post-treatment monitoring of lung transplant patients at risk of chronic lung allograft dysfunction. The award, totaling $248,999.00, will be provided to the University of Maryland, Baltimore to fund this 3-year research project from July 2025 to May 2028. The project aims to...
- This $292,500 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to identify novel microproteins associated with normal hematopoiesis and hematopoietic diseases. The project will leverage existing transcriptomic and translation data to produce a comprehensive catalog of microproteins expressed in different hematopoietic cell types. This inter-disciplinary research conducted by the Sanford Burnham Prebys Medical Discovery...