Project Grant K08DK139453
- This $2,971,227 federal Project Grant, awarded on September 4, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the role of fatty acids in regulating cellular metabolism and protein synthesis in the context of fasting, inflammation, and metabolic diseases. The research aims to uncover novel signaling pathways through which fatty...
- This $3,176,680 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research at the University of California, San Francisco (UCSF) to investigate the role of the scavenger receptor MARCO in regulating the balance between regulatory and immunogenic immune responses in the neonatal liver. The research aims to elucidate how MARCO expressed on liver macrophages...
- This $786,216 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on post-transcriptional regulation of hepatokines and their impact on systemic metabolism. The University of California, Los Angeles is conducting this research to investigate a novel mechanism by which the liver uses RNA-binding proteins to control the...
- This $2,833,514 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Renal Metabolism in AKI", will fund research to investigate changes in kidney metabolism in sepsis-associated acute kidney injury (AKI) and their impact on kidney tubule injury and recovery. The University of California, San Diego (UCSD) is the awardee...
- This Project Grant award of $1,982,628.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to develop advanced methods for detecting liver fibrosis and creating a predictive diagnostic model for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in primary care settings. The project aims to improve identification of...
- This $809,427 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on the impact of polymicrobial interactions and within-host adaptation on the pathogenesis of catheter-associated urinary tract infections (CAUTI). The award recipient, The Research Foundation For The State University Of New York (RF SUNY) doing business as Sponsored...
- This Project Grant award, in the amount of $126,846, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports a translational research project to investigate the role of the gut microbiome in the pathogenesis of sepsis-associated acute kidney injury (AKI). The research, to be conducted at the University of Michigan, aims to identify gut bacteria...
- This federal Project Grant award of $176,244 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to the University of California, San Francisco supports a 5-year research and training plan focused on the mechanisms underlying ciliary kidney diseases. The grant recipient, Dr. Gabriel Loeb, will investigate whether the transcription factor GLIS3 is regulated by the polycystin proteins and acts downstream of them to prevent kidney cyst formation. This work aims...
- This federal Project Grant award of $737,034.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The goal of this 5-year research project, with a start date of September 1, 2025, is to identify new regulatory inputs that control the biosynthesis of coenzyme A (CoA) in response to the metabolic state of cells and tissues, especially the kidney and liver. The...
- This federal Project Grant award of $147,486 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will fund research to investigate the role of gut microbes in regulating interleukin-22 (IL-22) levels in the pancreas and the impact on pancreatic health and disease. The research aims to determine how gut microbe-induced IL-22 affects pancreatic gene expression and the underlying cellular mechanisms, as well as the beneficial and detrimental effects of this...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is providing $173,664 to The Regents of the University of California, San Francisco (UCSF) to conduct research on "Molecular Characterization of Ascites Fluid to Identify Drivers of Infection in Patients with Decompensated Cirrhosis." The project aims to apply metagenomic next-generation sequencing and meta-transcriptomics to study the microbial composition and host response in ascites fluid from cirrhosis patients, in order to identify novel predictors of spontaneous bacterial peritonitis and mortality. The award has an initial period of performance from August 7, 2025 to July 31, 2030. This research aims to establish a comprehensive atlas of ascites microbial and serological attributes that could inform future interventions for cirrhosis patients at high risk of infection-related complications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $173.7k | 8/7/25 |