Project Grant K08CA293160

Award Date 7/2/25
Completion Date 6/30/30
Dollars Obligated $210K
Federal Grant Program
93.398
Assistance Type
Project Grant
Place of Performance
Texas, USA
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This federal Project Grant award, provided by the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), aims to evaluate dietary changes and a Mediterranean diet intervention among medically underserved men with prostate cancer.

The $210,003 award, effective July 2, 2025 through June 30, 2030, will fund a pilot feasibility study of a Mediterranean diet intervention targeting 25 men recently diagnosed with localized prostate cancer at a large safety net hospital. The project will first conduct focus groups with African American and Hispanic men diagnosed with prostate cancer to determine dietary habits and cultural factors related to diet. The adapted Mediterranean diet intervention will then be evaluated for feasibility of enrollment and implementation in this medically underserved population. The study will also assess noninvasive biomarkers, including a lipid-based signature and gut microbiome composition, for their association with dietary change. This research aims to identify potential markers of prostate cancer response to dietary intervention for future clinical trials.

The award will provide the principal investigator, who is based at the University of Texas MD Anderson Cancer Center, with training and mentorship in designing and administering behavioral interventions, health disparities research, and nutritional interventions, supporting their development as an independently funded surgeon-scientist focused on improving outcomes for medically underserved men with prostate cancer.

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