Project Grant K01DK140529
Award Date
8/1/24
Completion Date
5/31/29
Dollars Obligated
$470K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Boston, MA 02114, USA
Similar Awards
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Lynntech Inc. a $687,416 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop a cutaneous gel that can controllably deliver a small molecule therapeutic to effectively treat diabetic foot ulcers (DFUs). The project aims to (1) prepare and characterize a preferred gel formulation for controlled delivery, (2) further elucidate the therapeutic's...
This Project Grant award of $249,951 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop a novel tool called BACTVUE for the targeted ablation of infected bladder tissue in patients with antibiotic-refractory urinary tract infections (UTIs). The primary objectives are to demonstrate BACTVUE's ability to selectively stain diverse intracellular...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $268,377 to develop and evaluate a novel device for diabetic wound healing using high-frequency, low-amplitude vibration (HFLAV). The primary objectives are to: (1) enhance and validate the driver device by incorporating thermography to measure blood flow and tissue heat depth,...
The federal Project Grant award R43DK137607, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports the development of the "Smart Foot Mat" (SFM) by Eden Medical, Inc. The SFM is an in-home appliance that aims to monitor diabetic patients' foot oximetry and temperature to provide early detection of foot ulcers, a common and costly complication of...
Vivonics Inc., a medical technology company based in Massachusetts, received a $331,455 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to develop a near-infrared layered imaging system called NIR-LITH. This system aims to provide objective, three-dimensional hemodynamic mapping of diabetic foot ulcers and surrounding tissue with 1 mm depth resolution, improving clinicians' ability to assess wound healing potential and make more accurate...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Gelsana Therapeutics Inc., a woman-owned small business and HUBZone certified corporation, a $649,984 Project Grant (CFDA 93.847) on September 5, 2024. The grant supports the development of Provasliex Gel, a zwitterionic hydrogel that delivers controlled release of platelet-derived growth factor (PDGF) to promote wound healing and manage inflammation in diabetic foot ulcers. The goal is to demonstrate...
This $1,617,565 federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports research and development of a modular hybrid biomaterial delivery platform for short interfering RNA (siRNA) therapeutics. The overall objective is to construct a versatile, multi-functional lipoproteoplex (LPP) nanovehicle that can effectively...
This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...
The U.S. National Institute of General Medical Sciences (NIGMS) awarded a $435,226 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of Arkansas to develop a hyperstable and bioactive FGF1-FGF2 dimer formulation for effective healing of diabetic skin wounds. The project aims to: 1) Design a hyperstable and bioactive FGF1-FGF2 dimer and its variants; 2) Develop injectable anionic hydrogels to provide sustained release of the FGF1-FGF2 dimer; and 3)...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $990,990 Project Grant under CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research to Integrated Medical Sensors Inc. (IMS), a minority-owned small disadvantaged business in Irvine, CA. The objective is to optimize the manufacturing and quality framework for IMS's CGM+ continuous glucose monitoring platform, which uses miniaturized semiconductor-based electrochemical sensors to measure...