Project Grant K01AI201805
- The National Institute of Allergy and Infectious Diseases awarded the University of California, San Diego $480,000 on September 16, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the molecular basis for arboviral fitness in vector and reservoir hosts. The research examines how arboviruses replicate across evolutionarily distant hosts—insects and vertebrates—despite showing high specificity in their transmission cycles. Using alphaviruses as a...
- The National Institute of Allergy and Infectious Diseases awarded $765,496 to the University of California, Davis on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop recombinant enhanced antiviral restrictors (REAVRs) that broadly inhibit known and emerging viruses to control or prevent vector-borne and zoonotic viral diseases. The project will generate and optimize REAVR proteins by combining virus-sensing domains with effector domains from...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $455,692 to The Regents of the University of California, Berkeley under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 4, 2025, for a project concluding July 31, 2027. This Project Grant funds experimental research investigating the mechanisms underlying bat virus virulence and zoonotic spillover. The research employs experimental evolution of vesicular stomatitis...
- The National Institute of Allergy and Infectious Diseases awarded Yale University $655,316 on July 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate bat lyssavirus pathogenesis and entry mechanisms. The research addresses how lyssaviruses, including rabies virus, circulate in bat and mammalian species and spill over into humans at approximately 60,000 independent events annually. The project will systematically uncover how these viruses enter...
- The National Institute of Allergy and Infectious Diseases awarded The Regents of the University of California, San Francisco $787,837 on April 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and apply computational tools for assessing the risk that diseases with episodic transmission become established in the general population. The project will combine statistical inference with simulation approaches to extend methods for inference using branching...
- The National Institute of Allergy and Infectious Diseases awarded $234,151 to the University of California, Davis on August 14, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the mechanism of mRNA polyadenylation in immunoglobulin heavy chain genes during the differentiation of activated B cells into plasma cells. The research leverages single-cell-level RNA measurement coupled with RNA hybridization-based flow cytometry and CRISPR-based genome...
- The National Institute of Allergy and Infectious Diseases, part of the Department of Health and Human Services, awarded $235,500 to the University of California Irvine on February 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for Project Grant R21AI196970. The award funds research on the molecular architecture of the vaccinia virus factory, with emphasis on characterizing protein interactions at the molecular level during virion morphogenesis. The research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $438,500 Project Grant to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 8, 2025, with a completion date of June 30, 2027. This award funds investigator-initiated biomedical research examining the sequence-specific determinants and impacts of NS2 (nonstructural protein 2) interactions with the Influenza A Virus...
- The National Institute of Allergy and Infectious Diseases awarded La Jolla Institute for Immunology $279,000 on April 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to map anti-filovirus humoral immune responses in broadly seroreactive individuals. The award funds detailed analysis of antibody repertoires from 23 individuals in the Democratic Republic of the Congo who demonstrate extraordinarily broad and strong antibody responses against multiple filovirus...
- The National Institute of Allergy and Infectious Diseases, part of the Department of Health and Human Services, awarded the Scripps Research Institute $897,277 on June 25, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The recipient will conduct structural and functional research on monkeypox virus entry mechanisms and neutralizing antibody responses. The work integrates antibody isolation from mpox convalescents, vaccine recipients, and a human antibody phage...
The National Institute of Allergy and Infectious Diseases awarded the University of California, Davis $205,956 on August 14, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate paramyxoviruses circulating in bats in Puerto Rico and assess their spillover risk to humans and livestock. The project will develop pseudotyped viral reagents and stably transfected cell lines to quantify the entry potential of bat-borne paramyxoviruses across receptors for co-roosting bat, livestock, and human hosts. Longitudinal surveillance will identify temporal windows of viral shedding, assess ecological factors such as reproductive cycles and spatial overlap among host species, and evaluate opportunities for cross-species transmission, including interactions with pigs and other mammals. The work will characterize viral traits and ecological conditions that elevate spillover risk, with outputs intended to feed into risk characterization tools such as CEPI's VISTA platform and pandemic intelligence initiatives including NSF-CPI to support pandemic preparedness. The award provides mentored research experience for the principal investigator in molecular virology and ecological field surveillance under guidance from experts in viral ecology, molecular virology, and pandemic preparedness. Performance occurs in Davis, California, with a period of performance from August 14, 2026, through July 31, 2030. The assistance type is a project grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $206.0k | 8/14/26 |