Project Grant K01AI190048
- This Project Grant award of $197,640 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to assess the impact of spatial and social determinants on the risk and outcomes of invasive fungal infections (IFIs). The primary objectives are to: 1) determine neighborhood-level contextual and socioeconomic predictors of IFIs, and 2) examine the association between individual socioeconomic...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $616,588 to The Regents of the University of California, San Francisco (UCSF) to conduct research focused on "Exploiting a High-Precision Phenotypic Map to Illuminate Environmental Sensing by a Fungal Meningitis Pathogen." The goal is to develop a better understanding of the molecular function of unannotated genes in the fungal...
- This $750,815 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research conducted by the University of Maryland, Baltimore to investigate therapeutic targeting of the host hypoxia-response pathway to treat mucormycosis, a deadly invasive fungal infection. The research aims to explore alternative strategies beyond the currently limited treatment options for this disease, which has an unacceptably...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $438,038 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to The Regents of the University of California, doing business as the University of California, Berkeley (UC Berkeley). The award, dated July 15, 2025, will support a research project to study the molecular mechanisms underlying spore formation in the fungal pathogen Coccidioides, which causes the disease...
- This $147,486 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to investigate how the hypoxia morphology of the fungus Aspergillus fumigatus impacts diagnostic methods for invasive pulmonary aspergillosis (IPA). The research, conducted by Dartmouth College, will test the hypotheses that the hypoxia-associated gene HrmA regulates the composition of antigenic extracellular polysaccharides, and that...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $807,498 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Duke University. The award will fund research to understand the evolution of Cryptococcus neoformans strains and determine the underlying mechanisms responsible for their pathogenicity in HIV/AIDS patients. The research will leverage a comprehensive platform including a large global isolate repository, high-throughput...
- This National Science Foundation (NSF) Biological Sciences Program (CFDA 47.074) project grant in the amount of $240,000 will fund a postdoctoral research fellowship from July 1, 2024 to June 30, 2027. The research will investigate the environmental drivers of soil fungal pathogen spread, focusing on Coccidioides immitis, the pathogen that causes Valley Fever. The project aims to uncover the roles of landscape structure and local climate in shaping fungal pathogen distributions using genomic...
- This federal Project Grant award of $170,000 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The funding supports research by Prokaryotics Incorporated, a pharmaceutical and biotechnology company, to develop novel antifungal inhibitors targeting the glycosylphosphatidylinositol (GPI) ethanolamine phosphate transferase enzyme MCD4. This research aims to address the critical...
- The federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research program), aims to develop new antifungal agents targeting the fungal steryl-glucosidase (SGL1/SGLA) enzyme. The $782,178 award to The Research Foundation for The State University of New York, doing business as Stony Brook University, supports the following key efforts: High-throughput screening to identify chemical inhibitors of the fungal...
- The University of Tennessee Health Science Center (UTHSC) received a $121,752 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant will fund research to investigate the role of the SidB kinase and septation process in Aspergillus fumigatus, a fungus that causes the severe infection invasive pulmonary aspergillosis. The research aims to enhance the efficacy of echinocandin...
This $200,340 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support the career development of Dr. Brittany L. Morgan Bustamante, an infectious disease epidemiologist at the University of California, Berkeley. The research will investigate three clinically important invasive fungal diseases - aspergillosis, candidiasis, and cryptococcosis. The project aims to integrate electronic health record and national inpatient data with contextual indicators to identify multilevel drivers of fungal disease risk and severity. This will involve applying novel multilevel modeling approaches to estimate how fungal disease prevalence and mortality vary across individual characteristics, as well as using advanced spatial and multilevel methods to quantify the contributions of healthcare access, environmental conditions, and neighborhood indicators to fungal disease outcomes. The award has an initial term from August 2025 through July 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.3k | 8/22/25 |