Project Grant K01AG101560
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $125,766 Project Grant to The Leland Stanford Junior University effective July 1, 2026, through April 30, 2031, under the Aging Research program (CFDA 93.866). The research project investigates genetic and proteomic pathways linking Alzheimer's Disease (AD) to white matter hyperintensities (WMH), specifically examining how AD genetic liability drives WMH burden through circulating protein mediators. The study addresses a...
- Federal Grant Award Summary Award Details: The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a $331,776 Project Grant on August 15, 2025, under the Aging Research program (CFDA 93.866). The project, titled "Neuroimaging and Genetics of the Glymphatic System in Alzheimer's Disease," extends through May 31, 2030, and is being conducted in Palo Alto, California. Research Deliverables: The project will develop and validate novel, non-invasive...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a $770,000 Project Grant under the Aging Research program (CFDA 93.866) to conduct basic science research addressing postoperative delirium in geriatric populations. Awarded August 15, 2025, with completion scheduled for July 31, 2027, the project will investigate the central role of aldehyde dehydrogenase 2 (ALDH2) in regulating oxidative stress during anesthesia, with...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Stanford University a $646,340 Project Grant on June 15, 2026, under the Aging Research program (CFDA 93.866) to construct and analyze a novel individual-level database linking health trajectories of older adults to the physical, mental, and economic well-being of their family members. The primary deliverable is a comprehensive dataset covering twenty-five years (1999–2024) that leverages U.S. Census Bureau...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $1.24M Project Grant to The Leland Stanford Junior University to develop and analyze a novel individual-level database linking health trajectories of older adults to the physical, mental, and economic well-being of their family members across multiple generations from 1999 to 2024. The grant, obligated on September 30, 2025, under the Aging Research program (CFDA 93.866), addresses a significant gap in U.S....
- Grant Award Summary The National Institute on Aging (NIA) awarded a $423,500 Project Grant to The Leland Stanford Junior University, effective April 1, 2026, through March 31, 2028, under the Aging Research program (CFDA 93.866). The project, titled "Uncovering Dynamic Brain Circuit Mechanisms Associated with Apathy and Disinhibition in Alzheimer's Dementia," delivers research services focused on identifying mechanistic relationships between Alzheimer's disease (AD) pathology, brain...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a Project Grant of $149,190 under the Aging Research program (CFDA 93.866) on July 29, 2026, with a completion date of February 1, 2028. This grant supports the development and assessment of novel positron emission tomography (PET) radiotracers targeting G protein-coupled receptor 84 (GPR84) for imaging innate immune activation in Alzheimer's disease. The project addresses a critical...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Leland Stanford Junior University a Project Grant of $122,526 on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research initiative, titled "Delineation of Alzheimer's Disease Initiation and Propagation Using Novel Adult Human Brain Organoids," is scheduled for completion by April 30, 2028,...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $643,139 Project Grant to the University of California, Los Angeles, effective September 30, 2025, through August 31, 2027, under the Aging Research program (CFDA 93.866). The TARDIS-AD Project (Targeted Multi-Factorial Approaches to Reducing Disparities in Alzheimer's Disease) will deliver research services focused on identifying personalized intervention strategies to reduce health disparities in Alzheimer's disease...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded J. David Gladstone Institutes a Project Grant of $1,459,072 on August 1, 2025, under the Aging Research program (CFDA 93.866) to conduct research on Alzheimer's Disease (AD)-related neurological dysfunction. The research will deliver scientific knowledge and methodological innovations focused on understanding how inhibitory interneurons—specifically parvalbumin (PVALB) and somatostatin (SST) cell types—contribute...
The National Institute on Aging (NIA) awarded a Project Grant totaling $125,766 to The Leland Stanford Junior University beginning July 1, 2026, through April 30, 2030, under the Aging Research program (CFDA 93.866). The project, "Discerning the Molecular Mediators Between Cardiometabolic Risk Factors and Alzheimer's Disease," will identify molecular pathways linking cardiometabolic traits to Alzheimer's disease (AD) risk. Research outputs include identification of plasma protein and metabolite biomarkers that mediate cardiometabolic-AD pathways, replication analyses across large epidemiological cohorts (UK Biobank and Million Veteran Program), and genomic evidence for causal relationships between cardiometabolic traits and AD using Mendelian randomization approaches. The project comprises three specific research aims: (1) identifying plasma protein mediators of cardiometabolic traits and AD through proteomic mediation and causal analysis with replication in multiple AD cohorts; (2) analyzing plasma metabolite mediators using metabolomic data integrated with proteomics; and (3) estimating causal effects of cardiometabolic traits on AD through genotype-based Mendelian randomization. Deliverables include prognostic biomarker panels and research findings intended to enable development of new AD therapeutics targeting identified cardiometabolic pathways. The award supports research conducted at Stanford's Palo Alto, California location in alignment with NIA's mission to prevent and treat Alzheimer's disease and related dementias.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $125.8k | 7/1/26 |