Project Grant K01AA032313
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $550,417 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Texas at Austin. The grant, effective September 1, 2025 through May 31, 2030, supports research to investigate how heavy alcohol exposure in aging individuals leads to impaired microglia function, neurodegeneration, and cognitive deficits. The study aims to determine whether dysregulated neuroimmune and microglia responses are...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), has awarded a $410,413 Project Grant to Rutgers, The State University of New Jersey for the project "BLOOD BRAIN BARRIER DYSFUNCTION IN CHRONIC ALCOHOL USE DISORDER". The project aims to utilize a non-invasive MRI technique to map and determine the correlates of blood-brain barrier alterations in individuals with a history of severe chronic alcohol use disorder. The...
- This federal Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports research to investigate the effects of chronic intermittent alcohol exposure on orbitofrontal cortex (OFC) astrocyte physiology, structure, and gene expression, and how these changes contribute to altered OFC neuron excitability and excessive drinking behaviors. The $459,707 award, with a period of performance from September 5,...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $105,132 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Kentucky Research Foundation. The grant, titled "Uncovering the Functional and Mechanistic Dysregulation of Monocytes After Abstinence and Post-Abstinence Drinking," will leverage a rhesus macaque model to investigate the persistent functional, transcriptional, and epigenetic changes in peripheral monocytes induced by...
- The Project Grant award of $657,156.00 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), supports research to examine the role of BK channels in alcohol-induced dysmyelination. The project aims to investigate the structural and functional correlates of myelin protein changes in a mouse model of alcohol use disorder, focusing on the effects of alcohol on oligodendrogenesis and pre-existing myelin. Key objectives include using...
- This federal Project Grant award of $701,051 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273). The grant supports research to investigate the phenotypes and functions of distinct neutrophil populations in patients with severe alcohol-associated hepatitis (AH). Key objectives include: 1) Characterizing the transcriptomic profiles and functional roles of neutrophil subsets in AH using single-cell RNA sequencing; 2)...
- This federal Project Grant award of $2,552,568.00, awarded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) program, supports research to investigate the relationship between stress-induced neuroadaptations in the insula-BNST pathway and subsequent alcohol use disorder (AUD)-related behavior. The project, conducted by Wake Forest University Health Sciences, aims to elucidate how stress activation of AUD-associated...
- This Project Grant award of $303,737.00 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) to the University of Florida supports research to investigate the impact of chronic alcohol consumption on the development and progression of Alzheimer's disease (AD). The key objectives of this 2-year award, running from May 1, 2025 to April 30, 2027, are to: 1) assess the influence of chronic ethanol exposure on metabolic function and tau pathology in...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $136,236 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Washington on January 25, 2025. The grant project aims to investigate the synergistic effects of chronic alcohol use and pathological tau expression in a preclinical model, in order to better understand the neurodegeneration processes underlying Alzheimer's disease and related dementias (ADRD). Specifically, the research will...
- This federal Project Grant award for $700,000.00, issued by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program, supports research to investigate the neurophysiological and genetic factors contributing to binge drinking and alcohol use disorder. The primary awardee, the University of New Mexico (UNM) Health Sciences Center, will leverage techniques such as monosynaptic circuit labeling, optogenetics, electrophysiology,...
This federal Project Grant award in the amount of $178,513 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to Florida Atlantic University. The grant funds a research project titled "Peripheral Effectors in Alcohol-Induced Stress-Susceptibility and Blood-Brain Barrier Permeability" that aims to investigate how chronic alcohol exposure impacts the blood-brain barrier and contributes to stress-related behavioral alterations. The project will use a rodent model to characterize the role of neutrophil elastase and peripheral inflammation in mediating alcohol-induced disruption of the blood-brain barrier. Findings from this research are expected to provide insight into managing centrally-mediated dysfunctions resulting from alcohol abuse. The award period runs from September 17, 2025 through August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $178.5k | 9/17/25 |