Project Grant R21AA032105
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $550,417 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Texas at Austin. The grant, effective September 1, 2025 through May 31, 2030, supports research to investigate how heavy alcohol exposure in aging individuals leads to impaired microglia function, neurodegeneration, and cognitive deficits. The study aims to determine whether dysregulated neuroimmune and microglia responses are...
- This federal Project Grant award in the amount of $178,513 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to Florida Atlantic University. The grant funds a research project titled "Peripheral Effectors in Alcohol-Induced Stress-Susceptibility and Blood-Brain Barrier Permeability" that aims to investigate how chronic alcohol exposure impacts the blood-brain barrier and contributes to stress-related...
- The Project Grant award of $657,156.00 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), supports research to examine the role of BK channels in alcohol-induced dysmyelination. The project aims to investigate the structural and functional correlates of myelin protein changes in a mouse model of alcohol use disorder, focusing on the effects of alcohol on oligodendrogenesis and pre-existing myelin. Key objectives include using...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $733,704 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Lovelace Biomedical Research Institute in Albuquerque, New Mexico. The grant, titled "Multimodal Imaging of Prenatal Alcohol Exposure: Mechanisms Underlying Spatial Navigation Memory Deficits in Children and Adolescents," will fund a study to advance understanding of the neurophysiological mechanisms underlying spatial memory...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $601,129 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (CCLCM). The project, titled "Alcohol and Gut-Brain Axis and the Role of Butyrate on Neuroinflammation and Pain Sensitivity", aims to investigate the relationship between alcohol use disorder, chronic pain, and the gut microbiome, with a focus on the role of...
- This Project Grant award, valued at $2,250,249.00 and funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports a research project conducted by the University of California, San Diego (UCSD) to investigate brain features associated with alcohol use disorder (AUD). The project aims to employ longitudinal multi-parametric magnetic resonance imaging (MRI) to assess baseline brain characteristics and changes following alcohol...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) provides $248,959 to The Medical College of Wisconsin, Inc. to conduct research on the reciprocal relationship between alcohol use and brain function in adolescents and young adults. The 5-year project aims to assess how neurocognitive mechanisms of decision-making and risk-taking in adolescence contribute to alcohol use initiation, escalation, and maintenance,...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $105,132 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Kentucky Research Foundation. The grant, titled "Uncovering the Functional and Mechanistic Dysregulation of Monocytes After Abstinence and Post-Abstinence Drinking," will leverage a rhesus macaque model to investigate the persistent functional, transcriptional, and epigenetic changes in peripheral monocytes induced by...
- This federal Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports research to investigate the effects of chronic intermittent alcohol exposure on orbitofrontal cortex (OFC) astrocyte physiology, structure, and gene expression, and how these changes contribute to altered OFC neuron excitability and excessive drinking behaviors. The $459,707 award, with a period of performance from September 5,...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $136,236 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Washington on January 25, 2025. The grant project aims to investigate the synergistic effects of chronic alcohol use and pathological tau expression in a preclinical model, in order to better understand the neurodegeneration processes underlying Alzheimer's disease and related dementias (ADRD). Specifically, the research will...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), has awarded a $410,413 Project Grant to Rutgers, The State University of New Jersey for the project "BLOOD BRAIN BARRIER DYSFUNCTION IN CHRONIC ALCOHOL USE DISORDER". The project aims to utilize a non-invasive MRI technique to map and determine the correlates of blood-brain barrier alterations in individuals with a history of severe chronic alcohol use disorder. The research program will scan 30 recently detoxified individuals with chronic alcohol use disorder and 30 age/sex-matched controls to test the hypothesis that chronic alcohol use disorder is associated with reduced blood-brain barrier integrity. The project period runs from September 16, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $410.4k | 9/16/25 |