The long-term effect of HIV on medical readiness, duty-limiting medical conditions, and service retention

The Uniformed Services University of the Health Sciences awarded The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. a $859,020 Project Grant on September 1, 2025, under the Uniformed Services University Medical Research Projects program (CFDA 12.750). The three-year award, concluding August 31, 2028, funds research examining the long-term effects of HIV on medical readiness, duty-limiting medical conditions, and service retention among military personnel. The research advances the Department of Defense's mission to support military health and readiness by generating evidence-based knowledge on how HIV impacts military service capability and retention.

The project comprises two primary research aims. Specific Aim 1 employs difference-in-differences statistical modeling to determine the causal effects of HIV on military personnel's ability to fulfill their duties, with results disseminated through presentations, publications, and source code within the first 18 months. Specific Aim 2 develops multi-level dynamic models to elucidate pathways through which HIV affects military performance, incorporating biomarker analysis to estimate inflamm-age using serum repository specimens. The University of Idaho, through a sub-award issued November 26, 2025, provides statistical consultation and modeling expertise through Dr. Ridenhour and Dr. Vargas, while the Uniformed Services University supplies critical biomarker data collection to support model development and validation.