Project Grant HT94252510187

This Project Grant award from the Department of the Army Medical Command provides $3,940,561 to fund the "Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons with Chronic Spinal Cord Injury: The BO2ST Trial" project under the Military Medical Research and Development program (CFDA 12.420). The award period is from September 30, 2022 through September 29, 2026. The project aims to investigate the extent to which daily acute intermittent hypoxia...

This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $4,182,053.00 to The Spaulding Rehabilitation Hospital Corporation to conduct a clinical trial titled "Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery for Aging Adults with Chronic SCI: The BO2ST-II Trial." The award period runs from Sep 30, 2024 to Sep 29, 2028. The project will investigate using low-oxygen...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on evaluating the effects of spinal cord stimulation (SCS) interventions on bladder function after spinal cord injury (SCI). The $238,500 award, with a project period from December 2024 to November 2026, will support research conducted by the University of Pittsburgh to...

This federal Cooperative Agreement award, totaling $1,594,319.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Texas Health Science Center at Houston (UTHealth). The award aims to develop and test an innovative, non-invasive device called Breathing-Controlled Electrical Stimulation (BREESTIM) for the management of neuropathic pain after spinal cord injury. The project...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,354,442 Cooperative Agreement under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Texas at Dallas (UTD) on September 1, 2024. The project aims to develop a system integrating vagus nerve stimulation (VNS) with lower limb rehabilitation to enhance recovery of gait function in individuals with chronic spinal cord injury (SCI). The project's UG3...

This Project Grant award of $449,391.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at the University of Florida to develop combinatorial approaches to enhance breathing recovery after cervical spinal cord injury. The goal is to maximize breathing recovery by pairing therapeutic acute intermittent hypoxia with distinct respiratory training paradigms,...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA Program 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders", provides $427,625.00 to study whether electrical stimulation can enhance the capacity of neural stem cell transplants to improve recovery from chronic spinal cord injury. The primary goal is to determine if electrical stimulation supports the survival and differentiation of stem...

The Spinex Inc. was awarded a $4,719,091 Project Grant from the National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases to develop and clinically validate a transcutaneous electrical spinal cord neuromodulation (TESCON) device to mitigate symptoms of neurogenic bladder resulting from spinal cord injury. The award, made under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support Spinex in building a commercial...

This $450,213 National Science Foundation project grant will fund research at Loyola University of Chicago to develop a fundamental theory for using electrical modalities to enhance physical rehabilitation outcomes. Specifically, the grantee will investigate how best to use neuromodulation techniques to improve the results of neurorehabilitation by incorporating different electrical stimulation sequences. The research aims to provide insights into how peripheral nerve stimulation can assist axon...

This Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $274,841 to XN Health Inc. to develop a novel transtracheal phrenic nerve stimulation device. The device aims to reduce injury rates caused by mechanical ventilation by stimulating the phrenic nerves to induce diaphragmatic contractions, thereby increasing lung inflation and supporting protective ventilation for critically ill patients. The...