The National Institute of Neurological Disorders and Stroke (NINDS) awarded Drexel University a $405,625 Project Grant (R21NS131962) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The funding will support research to investigate the modular organization of respiratory control and changes in the respiratory system after cervical spinal cord injury (SCI) in freely behaving rats. The project aims to: 1) identify basic respiratory modules and...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA program 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders" will support research to investigate the use of normobaric oxygen therapy to mitigate inflammation and neuronal cell loss in spinal cord injury. The $595,245 award, running from August 2024 to May 2029, will be used by the University of Florida to conduct preclinical studies...
This Project Grant award from the Department of the Army Medical Command provides $3,940,561 to fund the "Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons with Chronic Spinal Cord Injury: The BO2ST Trial" project under the Military Medical Research and Development program (CFDA 12.420). The award period is from September 30, 2022 through September 29, 2026. The project aims to investigate the extent to which daily acute intermittent hypoxia...
This $391,250 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research aimed at developing effective therapeutic strategies for spinal cord injury (SCI) recovery. The key objectives are to: 1) Temporally regulate PTEN (phosphatase and tensin homolog) knockdown after SCI to promote axon regeneration while avoiding...
The Department of Defense's Military Medical Research and Development program (CFDA 12.420) awarded a $4,182,053 Project Grant to The Spaulding Rehabilitation Hospital Corporation in Boston, MA to conduct the "BREATHING LOW OXYGEN TO ENHANCE SPINAL STIMULATION TRAINING AND FUNCTIONAL RECOVERY FOR AGING ADULTS WITH CHRONIC SCI: THE BO2ST-II TRIAL". This 4-year grant, awarded on Sep 30, 2024, will support research to investigate the potential of combining acute intermittent hypoxia...
This $482,708 federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program supports research to restore breathing function in individuals with chronic cervical spinal cord injuries. The University of Florida will conduct a combined study of acute intermittent hypoxia and respiratory-triggered diaphragm pacing interventions, with the goal of developing new therapeutic approaches to improve breathing for this patient...
The Department of the Army Medical Command awarded Marquette University a $437,621 Project Grant under the Military Medical Research and Development (CFDA 12.420) program. The grant supports a 3-year research project titled "COMBINED THERAPEUTIC ACUTE INTERMITTENT HYPOXIA AND RESPIRATORY-TRIGGERED DIAPHRAGM PACING TO RESTORE BREATHING FUNCTION IN CHRONIC CERVICAL SPINAL CORD INJURY", running from September 30, 2025 to September 29, 2028. The research aims to develop innovative...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Ohio State University a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The $566,089 award, effective September 20, 2024 through August 31, 2029, supports research to understand the effects of pneumonia on spinal cord injury recovery. The project aims to identify circulating factors and spinal cord-specific mechanisms that...
This federal Cooperative Agreement award, totaling $2,354,442.00, was granted by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award aims to develop a system for closed-loop vagus nerve stimulation (VNS) therapy paired with lower limb rehabilitation to enhance recovery of gait function in individuals with chronic spinal cord injury (SCI). The...
This federal Project Grant award for $586,525.00, awarded on August 15, 2024 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports the development of a non-invasive infrared light therapy and medical device to treat spinal cord injury. The primary research aims to attenuate the acute injury and inflammatory response in the initial 24 hours following spinal...