This federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $1,163,218.00 to Case Western Reserve University's Office of Research Administration Division (doing business as University Hospitals of Cleveland) to conduct research on SLC37A3 as a novel prostate cancer target. The award period runs from July 15, 2024 to July 14, 2028. Through this funding, Case Western Reserve University will carry out...
The Department of Defense's Military Medical Research and Development program (CFDA 12.420) awarded Case Western Reserve University's Office of Research Administration Division, doing business as University Hospitals of Cleveland, a $1,467,210 Project Grant on September 30, 2024. The grant supports research to develop a novel dendritic cell therapy approach for mucosal melanoma, focusing on targeting a differentiation epitope in CD11b of tumor-associated inflammatory monocytes. The research aims...
The Department of the Army Medical Command awarded Case Western Reserve University a $1,288,000 Project Grant under the Military Medical Research and Development program (CFDA 12.420). The grant will fund research to therapeutically target superclusters at genes driving childhood sarcoma from September 2021 through September 2025. The Military Medical Research and Development program supports basic, applied, and advanced biomedical research to transform military and public health care through...
This federal Project Grant award from the Department of the Army Medical Command's Military Medical Research and Development program (CFDA 12.420) provides $872,237.00 to Case Western Reserve University to conduct research on pulmonary rehabilitation for advanced lung cancer survivors. The award has a performance period from May 1, 2025 to April 30, 2028. As a leading research university, Case Western Reserve University will leverage its extensive expertise in biomedical sciences, engineering,...
The U.S. Department of Defense (DoD) awarded a $497,747 project grant to Case Western Reserve University's Office of Research Administration Division (doing business as University Hospitals of Cleveland) under the Military Medical Research and Development program (CFDA 12.420). The grant supports the development of a novel, central nervous system-penetrant synthetic oleanane triterpenoid for the treatment of diffuse intrinsic pontine glioma (DIPG), a rare and aggressive form of pediatric brain...
This federal Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $606,869 to Case Western Reserve University to conduct research on mechanisms of androgen receptor inverse agonists in advanced prostate cancer. The project aims to map the epigenetic mechanisms driving metastatic castration-resistant prostate cancer (mCRPC) and develop small molecule inverse agonists that can functionally switch the androgen receptor to suppress tumor-driving...
This $779,983 Project Grant from the Department of the Army Medical Command supports the "DUAL-TRACER PET IMAGING TO TRACK LIVER CANCER THERAPY" research being conducted by Case Western Reserve University from August 1, 2022 to July 31, 2025. The grant falls under the Military Medical Research and Development program (CFDA 12.420), which aims to transform military and public health care through innovative biomedical research solutions for battlefield medicine. Case Western will use the...
This Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) is funding a $491,357 research project at Case Western Reserve University. The project aims to study the underlying mechanisms by which a small molecule activator of the mTORC1 signaling pathway can sensitize acute myeloid leukemia (AML) cells to proteasome inhibitors. Key objectives include mapping the mitochondrial respiratory lesions, identifying the mitochondrial stress...
Case Western Reserve University will receive $2,469,361 from the Department of the Army Medical Command under the Military Medical Research and Development federal grant program to support the SANGUISTOP project. This four-year Project Grant will fund research into intravenous nanomedicine for targeted thrombin delivery in hemorrhage control. The Military Medical Research and Development program aims to transform military and public health care through innovative medical solutions for...
The U.S. Department of Defense's Defense Health Agency awarded a $1,200,000 Project Grant to The Cleveland Clinic Foundation under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant funding supports research on "Therapeutic Strategies to Disrupt CX26-FAK-NANOG Complex to Attenuate Cancer Stem Cell Self-Renewal and Triple-Negative Breast Cancer Progression." The project will be carried out over a three-year period from May 1, 2025 to April 30,...