Project Grant HDTRA11610014

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support research at the University of Pittsburgh to study how host genetic factors influence susceptibility to Babesia microti infection, the primary cause of human babesiosis in the United States. The $250,573 award will fund a 2-year project to (1) assess how genetic differences in Collaborative Cross mouse strains impact parasitemia...

This Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research program), provides $228,435 to Arizona State University to investigate the biological mechanisms and genetic changes enabling a novel poxvirus variant called MYXV-TOL to cause a novel lethal disease in European rabbits. The two key objectives of this 2-year research project are to: 1) Elucidate how MYXV-TOL is causing a unique lethal disease in...

This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research to investigate the effects of spongy moth defoliation on blacklegged tick populations and the implications for tick-borne disease risk. The $179,544 award to the Cary Institute of Ecosystem Studies will fund experiments to evaluate how changes in ground-level temperature and humidity caused by spongy moth outbreaks impact the survival and population dynamics of...

This three-year project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $538,419 to the Los Angeles County Museum of Natural History Foundation to investigate the evolutionary drivers of host-parasite associations in mammal sucking lice. Through high-throughput sequencing, machine learning, genomic and morphological analyses, the project will generate the first phylogenomic tree for sucking lice, build a database of louse traits and...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $269,054 to the University of California, Merced to conduct research on host-parasite interactions and susceptibility mechanisms related to Toxoplasma gondii infection. The project aims to leverage the Collaborative Cross mouse model and parasite genetics to identify novel host genes and gene interactions that govern disease outcome...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $311,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. The grant, awarded on June 6, 2024, will support a project titled "Investigating the Mechanisms Underlying Mosquito Infectiousness in Malaria" through April 30, 2026. The project aims to determine the mechanisms driving the increased infectious potential of mosquitoes harboring...

This $483,851 award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support research at the University of Scranton to study factors influencing the prevalence of parasitic infections in birds. The project will collect and analyze parasite specimens from birds and insect vectors in northeastern Pennsylvania to test hypotheses about host traits and ecological interactions that drive parasitism. The research aims to advance understanding of disease...

This $1,447,376 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports a multidisciplinary research project titled "Beyond Discovery: Bat Behavior and Virus Shedding as Drivers of Spillover Risk." The project aims to investigate how bat behavior and virus shedding dynamics shape the risk of zoonotic disease spillover from bats to humans and livestock. The project will use longitudinal...

This $805,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to elucidate the tropism, receptor usage, and pathogenesis mechanisms of emerging pararubulaviruses, a group of bat-derived paramyxoviruses related to but distinct from human-specific viruses like mumps. The overarching goals are to: 1) Define the cellular tropism of Menangle and Sosuga viruses in human cells using organ...

The National Institute of Allergy and Infectious Diseases awarded a $720,456 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to the University of Washington to conduct research on "Disease Transmission Along Complex Human-Animal Networks: A Novel Method for Improving Zoonotic Disease Modeling". This 5-year project aims to characterize the structure and dynamics of human-animal contact networks across endemic zoonotic diseases like brucellosis, Q fever,...