Project Grant HC040398071

This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $390,000 to Thomas Jefferson University's Sidney Kimmel Medical College to evaluate the use of contrast-enhanced ultrasound (CEUS) and subharmonic-aided pressure estimation (SHAPE) techniques for assessing uterine fibroids before and after uterine artery embolization (UAE) procedures. The goal is to develop an...

This $437,461 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), funded under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a novel stabilization catheter device for His pacing lead implantation. The goal is to improve the accuracy and ease of His bundle pacing, an emerging alternative cardiac resynchronization therapy (CRT) for heart failure patients. The project aims to refine a deployable suction-tipped lead...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, provides $742,810 to the University of Virginia to develop hyperpolarized gas MRI (HGMRI) signatures for detecting and monitoring acute cellular rejection in lung transplant recipients. The 5-year project aims to correlate HGMRI signatures with tissue pathology, treatment response, and single-cell RNA-sequencing data to enhance early...

This $2,189,195 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to develop novel MRI tools to optimize surgical planning and improve fetal outcomes for twin-to-twin transfusion syndrome (TTTS). The key products and services to be delivered through this 5-year award include: Rapid 3D visualization of the placental surface vessels and...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $134,151 to the University of California, Irvine to develop a novel "metasurface optical guidewire" for use in percutaneous coronary intervention (PCI) procedures. The key objectives are to: 1) Design, develop, and manufacture the metasurface optical guidewire to precisely control intravascular laser dosimetry; 2) Develop a...

This federal Project Grant award of $308,526.00 from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research Program (CFDA 93.837), aims to develop a novel device for uterine hemostasis (stoppage of bleeding) after cesarean section procedures. The funded project seeks to finalize design parameters, validate materials, and conduct functional performance testing for this novel system, with the goal of enabling an early feasibility trial. Cesarean...

This Project Grant award of $3,422,481 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to develop a comprehensive genomic resource to characterize novel causes of unexplained recurrent pregnancy loss (RPL). The key products and services to be delivered under this 5-year award include: 1) leveraging the hospital's large clinical service for RPL and genetic research program to...

This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $598,983 to the University of Texas at Austin to develop a self-fitting vaginal stent to prevent post-radiation stenosis, a debilitating condition affecting up to 75% of patients who undergo pelvic radiation treatments. The funded research aims to design a shape-memory polymer vaginal stent that can expand to fit the...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,938,467 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program. The grant funds the development of a robot-assisted catheter placement system with a novel shape-sensing stylet to facilitate adaptive image-guided pelvic brachytherapy for gynecologic malignancies. Key objectives include: 1) creating a fiber-optic shape-sensing stylet for...

This federal Project Grant award from the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program provides $795,826 to Brigham & Women's Hospital Inc. to conduct research aimed at reducing variation and sociodemographic disparities in radiologist recommendations for additional medical imaging (RAI) and improving patient adherence. The key objectives are to: 1) Identify sociodemographic disparities in RAI rates,...