Project Grant FA95502410138

The National Eye Institute (NEI) awarded a $606,025 Project Grant (CFDA 93.867 Vision Research) to William Marsh Rice University to develop a high-resolution visual prosthesis using large-scale, ultraflexible electrodes to interface with the lateral geniculate nucleus (LGN) and restore visual function in blind individuals. The project aims to establish the feasibility and acquire key knowledge to build a lasting LGN visual prosthesis with unprecedented visual field coverage able to elicit...

The National Eye Institute (NEI) awarded a $1,765,704 Project Grant (CFDA 93.867 - Vision Research) to Trustees of Boston University to develop an injectable, high-precision optoacoustic retina prosthesis for minimally invasive stimulation of the retina. The key products and services to be delivered under this 3-year project include: Development of a highly efficient photoacoustic injectable biomaterial for retinal stimulation Demonstration of micrometer-scale (40-50 μm) resolution retinal...

This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $1,707,487 to the Regents of the University of Michigan to support research on intraretinal electrical stimulation for high-acuity artificial vision. The project aims to develop innovative approaches to enhance the spatial resolution and temporal control of retinal prostheses, with the goal of improving visual acuity and quality of life for patients with retinal...

This Project Grant award from the National Eye Institute (NEI), under the NEI Vision Research federal grant program (CFDA 93.867), will support research aimed at developing therapies to regenerate optic nerve connections and restore vision. The key objectives are to: 1) Evaluate the long-term functional recovery and integration of neural stem cell-derived neuronal relays in the injured optic nerve, 2) Investigate the role of developmental guidance cues in directing the growth of neuronal relay...

The National Eye Institute (NEI) awarded a $227,265 Project Grant (CFDA 93.867 Vision Research) to the University of California, Berkeley to map human retinal ganglion cell receptive fields and connect light stimulation of individual retinal photoreceptors to retinal ganglion cell activity and visual perception. The primary objectives are to: 1) leverage adaptive optics-stabilized microstimulation of the photoreceptor mosaic to precisely control input to the retina and disentangle the perceptual...

The National Eye Institute (NEI) awarded a $745,607 Project Grant (CFDA 93.867 - Vision Research) to Retivue LLC to develop the Retivue Entire Eye, a handheld, high-resolution, non-contact retinal screening camera for premature and healthy newborn babies. The goal is to create an affordable, easy-to-use device that can provide wide-field, high-quality retinal images in a single shot to enable more widespread screening for retinopathy of prematurity (ROP), a leading cause of preventable blindness...

The National Eye Institute (NEI) awarded a $881,796 Project Grant (CFDA 93.867 - Vision Research) to Siloam Vision, Inc. to develop and commercialize two advanced, laser-based, artificial intelligence (AI)-enabled retinal imaging systems. The goal is to address the unmet need for affordable, non-invasive pediatric retinal imaging to detect and diagnose retinopathy of prematurity (ROP), a leading cause of child blindness. The key innovations include an ultrawide-field (up to 165 degrees) camera...

This $1,177,273 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) supports research to understand the principles of phosphene fusion, which occurs when electrical stimulation of the visual cortex generates a single, merged perception of light rather than distinct points of light. The University of Pittsburgh, the grant recipient, will conduct detailed electrophysiology studies in monkeys to develop a...

This Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) aims to develop a novel ultra-high-speed volumetric imaging system capable of capturing the full electrical dynamics of thousands of neurons in the cortex and hippocampus of awake, behaving rodents. The $259,095 award to Rockefeller University will leverage structured one-photon excitation and advanced light field detection to achieve the temporal resolution needed to record single...

The National Eye Institute (NEI), part of the National Institutes of Health, awarded a $331,131 Project Grant under the Vision Research program (CFDA 93.867) to Physical Sciences Inc. (PSI) to develop and validate a high-resolution retinal imaging system with light flicker capabilities. This system aims to enable objective characterization of the photoreceptor response to light and quantify differences between normal and diseased eyes, particularly for patients with diabetic retinopathy. PSI,...