The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $147,656 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Medical College of Wisconsin, Inc. to conduct a multi-disciplinary analysis of the role of the PagC protein in outer membrane vesicle (OMV) biogenesis in Salmonella Typhimurium. The research aims to define the molecular mechanisms by which PagC induces positive membrane curvature to facilitate OMV production, utilizing an integrative approach of biophysical, biochemical, ultrastructural, and microbiological techniques. The project is expected to run from May 2025 to November 2027 and may provide a framework for understanding OMV biogenesis in other bacterial species.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $73.8k | 11/12/24 | ||
| Not listed | $0 | 11/12/24 | ||
| Not listed | $73.8k | 11/12/24 |