This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $590,742 to The Johns Hopkins University to develop a novel human laboratory model for studying resilience among individuals with opioid use disorder (OUD). The goal is to validate a set of resilience laboratory tasks that can assess psychological, cognitive, and affective resilience in people with OUD under stress and non-stress...
The National Institute on Drug Abuse (NIDA) awarded a $2,902,673 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Rutgers, The State University of New Jersey, with a sub-award to The Washington University. The grant aims to establish OPRM1 exon 7-associated variants as novel therapeutic targets for mitigating adverse effects of clinically used mu opioids, such as fentanyl and oxycodone, without altering their analgesic properties for pain management. The research...
This $1,539,260 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support research to understand the role of the kappa opioid receptor (KOR) system in opioid use disorder (OUD). The key objectives are to: 1) Compare KOR availability between early abstinent individuals with OUD and healthy controls using PET imaging; 2) Examine how individual differences in KOR availability relate to post-inpatient opioid use...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to evaluate a novel combined treatment approach of guanfacine and mindfulness meditation as an adjunct to buprenorphine maintenance for individuals with opioid use disorder (OUD). The $1,264,863 award to Rutgers, The State University of New Jersey, with sub-awards to the University of California, San Diego, and Indiana University, will...
The National Institute on Drug Abuse (NIDA) awarded a $431,750 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Rutgers, The State University of New Jersey. The grant, titled "Informing National Overdose Prevention and Treatment Strategies for High-Risk Adolescents," aims to generate evidence on individual and clinical care factors associated with adolescent drug overdose risk. The key objectives are to: 1) Estimate the prevalence of adolescent nonfatal...
This federal Project Grant award, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop advanced statistical methods and software for analyzing harmonized data from multiple clinical trials for treating opioid use disorder. The key objectives are to: 1) create efficient estimators for average treatment effects, conditional average treatment effects, and optimal individualized treatment rules in multi-study,...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to modify the Opioid Use Disorder (OUD) Cascade of Care model to better reflect the changing landscape of real-world OUD treatment. The $459,045 grant, awarded on September 30, 2024, will enable the prime awardee, the RAND Corporation, to link data from healthcare, substance use treatment, prescription drug monitoring, and mortality systems...
This $155,140 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports research conducted by Rutgers University to explore the relationships between substance use disorders (SUDs) and other forms of psychopathology. The goal is to improve classification and prediction of treatment response for SUDs by better understanding their phenotypic and genetic overlap with other psychiatric conditions. The research...
This federal Project Grant award of $4,319,168.00 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to Yale University. The award, effective July 1, 2024, supports a research project titled "Functional Connectivity Mechanisms of Opioid Abstinence" with a planned completion date of April 30, 2029. The project aims to advance scientific understanding and treatment of opioid use disorder (OUD), a significant public...
This federal Project Grant award, with ID R25DA061485, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $524,272 award will fund the development of the "Training in Research Undergraduate Experience through the Rutgers Addiction Research Center: The TRUE RARC Scholar Program" at Rutgers, The State University of New Jersey. The program aims to promote the advancement of students from underrepresented groups...