Project Grant F31AA033248
- Federal Grant Award Summary Brown University received a $733,137 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 18, 2025, with a completion date of August 31, 2030. The award funds a 12-week, double-blind, randomized controlled trial (RCT) evaluating probenecid as a pharmacological intervention for alcohol use disorder (AUD). The study will enroll 120 individuals with AUD and test...
- Federal Project Grant Award Summary Brown University received a $2.15 million Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 25, 2025, through August 31, 2029. The award supports fundamental neuroscience research investigating the circuit and molecular mechanisms through which alcohol influences natural reward systems. The research will utilize the Drosophila model organism to...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) awarded a Project Grant of $140,340 to The Regents of the University of Colorado–Denver, with performance from December 1, 2025, through June 30, 2028. The research project investigates the role of the C5 complosome in ethanol-induced immunometabolic dysregulation of Kupffer cells in alcohol-associated liver disease (ALD). Specifically, the research will...
- Federal Project Grant Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $249,000 to Indiana University Indianapolis on September 12, 2025, under the Alcohol Research Programs (CFDA 93.273) to support a three-year research project concluding August 31, 2028. The award funds mechanistic research investigating the role of neutrophilic NCF1 (p47phox) in alcohol-associated liver disease (ALD) pathogenesis. The research addresses a critical gap in understanding how...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Boston University Medical Campus a Project Grant of $580,556 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct mechanistic research examining the role of pituitary adenylate cyclase activating polypeptide (PACAP) in heavy alcohol drinking and associated anxiety-like behavior. The research employs animal models of heavy alcohol drinking combined with pharmacological,...
- Federal Project Grant Award Summary The Medical University of South Carolina received a $154,300 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective June 1, 2026 through October 15, 2028. The award funds a research project titled "Neuroplasticity as a Mechanistic Link Between Adversity and Alcohol Use in Adolescence," which leverages data from the Adolescent Brain Cognitive Development Study to...
- Federal Grant Award Summary Brown University received a $394,604 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 25, 2025, with completion targeted for August 31, 2028. The project develops and validates virtual reality (VR) technology as an adjunct to cognitive behavioral therapy (CBT) for adults with alcohol use disorder (AUD). The deliverable consists of immersive VR experiences designed...
- Federal Grant Award Summary Wake Forest University Health Sciences received a $2.55 million Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 5, 2025, with completion targeted for August 31, 2029. The grant supports research investigating the insula-bed nucleus of the stria terminalis (BNST) neural circuit's role in regulating alcohol use disorder (AUD). The research project focuses on...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $248,770 under the Alcohol Research Programs (CFDA 93.273) to The Research Foundation for the State University of New York on September 25, 2025, for a project period extending through August 31, 2028. This K99/R00 career development award supports research examining emotion regulation strategy use as a transdiagnostic treatment mechanism in an outpatient program for adolescents with co-occurring...
- Federal Grant Award Summary Auburn University received a $629,828 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 20, 2025, with a completion date of August 31, 2030. The grant supports a multimodal research initiative examining neural, neuroendocrine, and immune responses to alcohol-related cues in individuals who engage in binge drinking. The research aims to develop and validate a...
Brown University received a $100,228 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded November 10, 2026, with completion targeted for July 31, 2028. This F31 (predoctoral fellowship) research project investigates the convergent effects of alcohol use and adverse childhood experiences (ACEs) on immune dysregulation. The study leverages existing biological and behavioral data from the Center for Addiction and Disease Risk Exacerbation (CADRE), including plasma cytokine measurements (IL-6, TNF-α, MCP-1, IL-10), Timeline Follow Back alcohol and substance use data, and ACE exposure scores from study participants. The project deliverables consist of two primary research aims: (1) examination of dose-dependent associations between three alcohol use metrics and immune biomarkers including individual cytokines and their ratios, and (2) evaluation of whether ACE exposure moderates alcohol-inflammation associations. The research addresses gaps in current literature by employing refined alcohol consumption metrics that capture dose-response and temporally proximal use patterns, along with comprehensive immune biomarker panels that distinguish compensatory from maladaptive immune responses. Findings will contribute to understanding shared biological mechanisms underlying alcohol's contribution to chronic disease outcomes including liver disease, cardiovascular dysfunction, neurodegeneration, and cancer.Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $50.1k | 6/16/26 | ||
| Not listed | $0 | 6/16/26 | ||
| Not listed | $50.1k | 6/16/26 |