Project Grant DP2MH140134
Award Date
9/4/24
Completion Date
9/3/27
Dollars Obligated
$1.3M
Funding Federal Agency
Office of the Director
Awarding Federal Agency
National Institute of Mental Health
Federal Grant Program
93.310
Assistance Type
Project Grant
Place of Performance
Tennessee, USA
Similar Awards
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $543,337 to Vanderbilt University to support research on long-distance regressive signaling and its role in nervous system development. The research aims to characterize the features of the p75 neurotrophin receptor (p75NTR) in regressive signaling processes like apoptosis, axon...
This $382,436 Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the mechanisms regulating the synthesis, sorting, trafficking, and release of neuropeptides from dense core vesicles within neurons. The project aims to create new transgenic fly lines to directly visualize these intracellular processes in vivo using advanced microscopy techniques. Key...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $481,250 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to President and Fellows of Harvard College. The grant's objective is to develop a synthetic biological system that can manipulate subcellular RNAs and proteins in a subtype- and context-specific manner within neurons. This system aims to enable novel investigations of how subcellular...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), will support research to map the functional G protein-coupled receptor (GPCR) diversity in neurons and investigate the spatiotemporal signaling consequences. The $597,844 award, effective September 1, 2024 through March 31, 2027, will be provided to the Regents of the...
The National Institutes of Health (NIH) Office of the Director awarded a $1,345,424 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Regents of the University of Michigan. The grant, effective September 10, 2024 through September 9, 2027, aims to develop a novel genetically encoded "protein ticker tape" system that enables long-term, brain-wide recording of single-cell physiology in live mice without external interfacing. The technology will leverage...
The National Institute of General Medical Sciences (NIGMS) awarded Vanderbilt University a $395,943 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) with a performance period from September 1, 2024 to August 31, 2029. The goal of this research program is to develop new spectroscopic methods capable of providing enhanced insight into protein structure and dynamics within complex environments that impact human health. The key products and services to be...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $422,280 to support research on the molecular mechanisms underlying the nanoscale organization of the neurexin family of presynaptic cell-adhesion proteins. The 2-year project, commencing on April 1, 2025, aims to use advanced super-resolution imaging techniques to investigate how the intracellular protein p130Cas regulates the distribution...
This $660,632 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to understand the dynamics and structure of synaptic vesicle fusion pores. The objectives are to: Leverage a novel system that enables millisecond-scale measurements of single, reconstituted fusion pores to study their regulation, structural transitions, and...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $404,340 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Georgia Research Foundation, Inc. The project aims to develop a novel method using split fluorescent protein tags to map the localization of neurotransmitter receptors within neural circuits in the Drosophila model organism. This work will provide crucial new insights into the...
This Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $3,946,385 to Vanderbilt University to develop novel analytical approaches to dissect cell-cell communication among microglia, astrocytes, and neurons, and how these communications are dysregulated during Alzheimer's disease (AD) progression. The award period is from Aug 1, 2024 to Apr 30, 2029. Vanderbilt University Medical Center and Emory University have been awarded sub-grants to...