This $3.474 million project grant from the National Institutes of Health Trans-NIH Research Support program was awarded to the Max Planck Florida Corporation, doing business as the Max Planck Florida Institute For Neuroscience, to support research into neuronal mechanisms that shape brain computations and flexible behaviors. The grant period runs from September 2022 through August 2025. Specifically, the project aims to establish experimental methods to examine neuronal dynamics and synaptic...
The National Institutes of Health (NIH) awarded a $1,385,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Allen Institute, a non-profit research organization, to develop novel techniques for measuring the input-output operations of individual neurons in the mouse cortex. The project aims to overcome challenges in understanding how neurons in the mammalian brain transform their synaptic inputs into outputs, which is critical for designing effective brain-machine...
This $1,127,000 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) will fund a transformative research program at Duke University to map and dissect the brainstem central pattern generators that coordinate orofacial rhythms such as licking, breathing, and swallowing. The project aims to use large-scale high-density electrophysiology mapping, circuit tracing tools, and simultaneous recording and...
This $1,345,424 project grant awarded by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) aims to develop a novel "protein ticker tape" technology that enables long-term, brain-wide recording of single-cell physiology in living mice. The University of Michigan, the prime awardee, will leverage expertise in protein engineering and neurotechnology to create genetically encoded protein assemblies that can store and...
This Project Grant award, issued by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to understand the energy supply mechanisms that enable learning and memory formation. The $1.737 million award, spanning from Sep 1, 2024 to Aug 31, 2027, will fund research at the Max Planck Florida Institute for Neuroscience to investigate how spatially stable mitochondria in neuronal dendrites provide localized ATP production to support...
This $6,675,787 Cooperative Agreement award, granted by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports the development and optimization of genetically encoded indicators for simultaneously measuring neurotransmitter release, neuromodulator diffusion, and neuronal activity in live animals. The primary awardee, Max Planck Florida Corp, is collaborating with researchers from Stanford University, UC Davis, University of Southern...
This Project Grant award from the National Institutes of Health (NIH) Office of the Director, under the Trans-NIH Research Support program (CFDA 93.310), provides $1,271,280 to the Allen Institute in Seattle, Washington to develop two "exa-scale tissue readout methods" that will dramatically improve throughput for high-resolution, highly multiplexed imaging of large tissue volumes. The first platform aims to enable molecular-scale mapping of individual proteins across entire brains,...
The U.S. National Institutes of Health (NIH) Office of the Director awarded a $1.33 million Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Salk Institute for Biological Studies in La Jolla, CA. The grant, awarded on September 12, 2024, will fund a 5-year research project to develop a system for the targeted degradation of extracellular proteins in the brain in order to enhance neuronal plasticity and enable controlled synaptic remodeling and repair. The project...
The National Institutes of Health (NIH) Office of the Director awarded a $2,156,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Regents of the University of Minnesota. This 5-year grant, with a start date of September 30, 2024, aims to develop and validate novel neuroimaging methods for non-invasively measuring brain oxygen availability, pH, and carbon dioxide levels. The goal is to better understand the relationship between neurovascular coupling, metabolic...
This $1,255,340 Project Grant awarded by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) supports research to understand how the brain processes somatosensory feedback to enable dexterous movement control. The primary awardee, the University of California, Berkeley, will use simultaneous high-density neural recordings in the motor cortex, somatosensory cortex, and motor thalamus of non-human primates to investigate how...