Project Grant DESC0025892

This $1.1 million Project Grant from the National Science Foundation's Mathematical and Physical Sciences program will fund the acquisition of a magnetic-field-free atomic-resolution scanning transmission electron microscope at the University of Illinois at Chicago from September 2022 through August 2025. The microscope's novel lens design provides a magnetic-field-free sample region allowing for atomic-resolution imaging and chemical analysis of quantum materials such as magnetic,...

This $750,000 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a Leica Stellaris 8 DIVE multiphoton microscope system for the UC San Diego School of Medicine Microscopy Core. The new multiphoton microscope will replace the previous inoperable system and provide cutting-edge imaging capabilities to support a broad range of NIH-funded biomedical research projects across the university. The...

This federal Project Grant award from the U.S. Department of Energy Office of Science (CFDA 81.049 Office of Science Financial Assistance Program) provides $256,500.00 to Mizar Imaging LLC, a for-profit limited liability company, to develop an automated light sheet illuminator system compatible with super-resolution and single-molecule imaging techniques. The award period runs from February 12, 2024 to November 11, 2024. Through this project, Mizar Imaging LLC will create an advanced...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Macula Vision Systems Inc., a for-profit organization, supports the development of a novel microscopy platform to automate the interpretation of microbiology lab tests performed in hospitals. The project aims to address the shortage of trained lab technicians by engineering a specialized light source, customized camera, and AI-enabled algorithms to analyze...

The University of Michigan was awarded a $1.8 million project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program to purchase a Leica SP8 confocal microscope. The microscope will support over 30 investigators at the University engaged in diabetes, vision, and retinal research by replacing two aging microscopes in the university's shared imaging facility. The new microscope will provide high-speed resonant scanning...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Small Business Innovation Research (SBIR) Phase I project award of $274,998 to Magnify Biosciences Inc. aims to develop an automated "AutoMagnify" device that physically expands biological specimens up to 1,000 times in 3D while preserving spatial and molecular integrity. This advancement will enable conventional light microscopes to achieve nanoscale imaging resolution capabilities...

This $573,147 National Science Foundation Project Grant through the Integrative Activities program (CFDA 47.083) will fund the acquisition of a Zeiss LSM 900 confocal microscope with Airyscan for Queens College of the City University of New York's Core Facility for Imaging, Cell, and Molecular Biology. The microscope will enhance multidisciplinary research and training at the minority-serving institution by enabling new microscopy courses and outreach activities promoting STEM access for...

This Project Grant award from the National Science Foundation's Integrative Activities program (CFDA 47.083) provides $476,440 to the University of South Alabama to acquire a dual inverted selective plane illumination microscopy (diSPIM) light sheet system. The diSPIM system enables rapid, high-resolution imaging of large biological samples with minimal photodamage, allowing simultaneous measurement of intracellular signals and protein localization across complex model systems. This advanced...

The University of California, San Diego (UCSD) was awarded a $587,425 Project Grant from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to develop the first dual-modality super-resolution microscopy system, termed Dual-Modality Localized Plasmonic Structured Illumination Microscopy (DM-LPSIM). This new imaging technology will enable simultaneous high-speed super-resolution fluorescence and label-free scattering imaging at the 50-nanometer scale. The DM-LPSIM system...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a 3-year, $450,000 Project Grant to The Washington University to develop a novel "Plasmon-Enhanced Expansion Fluorospot" (PEEFS) technology. This bioplasmonic imaging method combines fluorescent nanoparticles and expansion microscopy to enable highly sensitive and high-resolution monitoring of cell-secreted proteins at the single-cell level. Key project objectives...