Project Grant 2316285
- This National Science Foundation (NSF) Project Grant award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 in funding to Nanores LLC for the development of a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues at nanoscale resolution and depths up to 250 micrometers. The project aims to advance fluorescence imaging capabilities to enable breakthroughs in drug discovery, disease...
- This $475,670 CAREER Project Grant awarded by the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041) aims to develop a new method for tracking molecular changes in live tissue over time. The project will focus on creating a nanostructure-based system to continuously monitor cellular activity and interactions, which can help improve understanding of cellular behavior and advance medical treatments, particularly for complex...
- This $531,227 CAREER award from the National Science Foundation's (NSF) Engineering program to the University of California, Irvine (UC Irvine) aims to develop a new "OptOGel Proteomics" technique for high-resolution analysis of subcellular protein localization and function. The project will focus initial validation on mapping the nuclear lamina, a cellular structure implicated in cancer and aging. The research seeks to overcome limitations of current spatial proteomics tools by...
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia Institute of Technology in the amount of $861,467 starting on September 1, 2025 and ending on August 31, 2028. The purpose of the grant is to enable research and educational infrastructure innovations in biophotonics and advanced microscopy. The research goal is to develop and implement Parallel Multifocal Scanning Microscopy (PMS), a super-resolution imaging technique...
- The National Science Foundation awarded the University of Louisville a $358,793 project grant under the Biological Sciences program (CFDA 47.074) to develop a microfluidic platform for dielectric characterization of biological nanoparticles. A team of graduate, undergraduate, and high school students will design and build the system using microfabrication techniques, gaining entrepreneurial training through university programs. The specialized platform will enable fundamental insight into...
- The National Science Foundation (NSF) awarded a $630,000 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to the University of New Mexico (UNM) to develop an advanced optical microscopy system. The project aims to significantly improve the study of protein clustering and interactions on cell membranes, which could advance the understanding of cell signaling and related diseases like cancer. The highly interdisciplinary research will combine the MINFLUX and modal...
- The National Science Foundation (NSF) Directorate for Engineering (ENG) awarded a $300,000 Project Grant to Kansas State University to develop a novel Electromicrofluidic (EMF) biosensing platform for comprehensive gene expression profiling. The 3-year project aims to create an automated system that can simultaneously analyze multiple protein isoforms and RNA splicing variants at the single-cell level, providing insights into complex biological processes involving cell-cell interactions and...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) will provide $649,999 to Northwestern University to develop a new label-free nanoimaging platform called 3D DNA Spectroscopic Photon-Localization Intrinsic-Contrast Nanoscopy (3D DNA-SPIN). The goal is to image the genome of intact fixed cells in 3D with 2-nanometer resolution, providing chemical and molecular information without the need for fluorescent labels. The project aims to 1) develop...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 Project Grant to The Pennsylvania State University, doing business as Penn State, for the project "COLLABORATIVE RESEARCH: MULTIMODAL MAPPING OF GENE ISOFORMS BY ELECTROMICROFLUIDIC MANIPULATION". This project under the NSF Engineering program (CFDA 47.041) aims to develop an Electromicrofluidics (EMF) technology platform that can simultaneously analyze...
- This $373,344 federal Project Grant award from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports a collaborative research project led by Professors Julie Biteen of the University of Michigan and David Masiello of the University of Washington. The project aims to develop a multifunctional, high-sensitivity instrument to measure plasmon-enhanced chirality and enable the sensing of subtle, heterogeneous...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a 3-year, $450,000 Project Grant to The Washington University to develop a novel "Plasmon-Enhanced Expansion Fluorospot" (PEEFS) technology. This bioplasmonic imaging method combines fluorescent nanoparticles and expansion microscopy to enable highly sensitive and high-resolution monitoring of cell-secreted proteins at the single-cell level. Key project objectives include realizing multiple plasmonic-fluor nanoparticles, demonstrating the PEEFS imaging and quantification capabilities, and developing multi-color PEEFS for analyzing cell surface and secreted proteins. This transformative technology aims to advance understanding of cell-to-cell heterogeneity and protein secretion dynamics, with applications in immunology, oncology, and stem cell biology. The project also provides training and outreach opportunities for graduate, undergraduate, and K-12 students in STEM fields related to plasmonics, super-resolution microscopy, and optical bioimaging.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.0k | 7/20/23 |