Project Grant C06OD039870
- This Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $3,999,041 to the Tulane National Primate Research Center (TNPRC) at Tulane University to expand its specific pathogen-free (SPF) rhesus macaque breeding colony. The funding will support the construction of new indoor/outdoor enclosures to house and breed the SPF rhesus macaques, which are a critical resource for NIH-funded...
- This Project Grant award of $437,250.00 from the National Institutes of Health (NIH) under the Trans-NIH Research Support (CFDA 93.310) program supports research to investigate the roles of specific CD4 T cell subsets, namely T helper 1 (Th1) cells and T central memory (TCM) cells, in driving neuroinflammation associated with HIV. The research aims to assess the impact of blocking the infiltration of these CD4 T cell subsets into the central nervous system (CNS) to reduce viral loads and...
- This $382,500 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program, is to support research on the role of nuclear cyclic GMP-AMP synthase (cGAS) in the DNA sensing signaling pathway and elucidate the regulatory mechanisms of nuclear cGAS. The research will investigate three key aims: (1) determining the mechanisms controlling cGAS nuclear localization and activation, (2) elucidating...
- This $457,778 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the development of a human microphysiological system (MPS) to investigate the peripheral nervous system (PNS) neurotropism of respiratory syncytial virus (RSV) and SARS-CoV-2. The research aims to elucidate the underlying mechanisms contributing to chronic neurological impairments associated with RSV and...
- This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $887,626 to the University of Miami to conduct research focused on preventing immune responses towards adeno-associated virus (AAV)-delivered anti-HIV antibodies. The project aims to explore two strategies to induce tolerance and prevent anti-drug antibody (ADA) formation in response to AAV-mediated gene therapy delivering broadly neutralizing HIV...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $2,505,639 to support research on the replication and evolution of primate lentiviruses. The research aims to establish the molecular-level details of interactions between lentiviral capsids and the RBD4-CHD didomain of the nuclear pore complex component NUP358, and how this affects viral nuclear import and...
- This $823,691 Project Grant award was provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) to investigate the role of immune checkpoints in the central nervous system (CNS) of people living with HIV (PLWH) and their association with HIV-associated neurocognitive disorder (HAND). The research aims to determine the profiles and biological functions of soluble immune checkpoints (sICPs) in the CNS of PLWH and a simian immunodeficiency...
- The Defense Health Agency (DHA) awarded a $300,000 Project Grant to The Administrators Of Tulane Educational Fund, doing business as Tulane University, under the Military Medical Research and Development program (CFDA 12.420). The grant, titled "Determining Risk for Lupus Nephritis Through the Intersection of Glycobiology and Immunometabolism," aims to conduct advanced biomedical research to transform healthcare for military service members, veterans, and the broader public. The...
- The National Institutes of Health's National Institute of Allergy and Infectious Diseases awarded a $2.3 million Project Grant to the University of California, Davis to fund research targeting CD4 T follicular helper cells for enhancing HIV vaccine-induced humoral immunity. The two-year award, issued on May 12, 2021 under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support preclinical studies in rhesus macaques to better understand the immunological mechanisms...
- This $382,500 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to determine the role of the TXLNA protein in the STING-mediated activation of the TBK1 signaling pathway, which is critical for the innate immune response to cytosolic DNA. The research will employ a mouse knockout model to investigate how TXLNA regulates this pathway and its implications for...
The U.S. Department of Health and Human Services National Institutes of Health (NIH) awarded a $3,999,180 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Administrators Of Tulane Educational Fund, doing business as Tulane University. This grant will fund the expansion of indoor-outdoor housing facilities for Tulane's Specific Pathogen-Free (SPF) Macaque Breeding Colony to support HIV/AIDS-related research at the Tulane National Primate Research Center (TNPRC). The project will enhance animal protection, increase group housing flexibility and capacity, and incorporate innovative environmental enrichment features. This infrastructure investment aims to address the growing demand for nonhuman primates in biomedical research, as highlighted in recent NIH-commissioned studies. The project will be completed by May 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.0m | 9/15/25 |