Project Grant 84082701
- The National Science Foundation (NSF) awarded a $949,997 Project Grant to Iowa State University of Science and Technology under the Biological Sciences program (CFDA 47.074) to investigate the role of environmental factors in the development of antimicrobial resistance (AMR) in municipal wastewater treatment plants. The five-year research project, starting November 1, 2023, will conduct field, laboratory, and computational studies to determine how susceptible bacterial strains are replaced by...
- This $650,000 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) to Virginia Polytechnic Institute & State University (Virginia Tech) supports research to investigate the role of environmental factors in the development of antibiotic resistance among bacteria in municipal wastewater treatment plants. The key products and services to be delivered under this 5-year award include: Conducting integrated field, laboratory, and computational studies to...
- The National Science Foundation Division of Emerging Frontiers awarded a $1,400,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Research Foundation For The State University Of New York, also known as Sponsored Projects Services, a non-profit research administration organization. This 5-year grant will fund collaborative research to investigate the role of environmental factors like temperature, heavy metals, and other contaminants in the development of...
- This Project Grant award, totaling $620,000.00, was provided by the U.S. Geological Survey (USGS) under the Assistance to State Water Resources Research Institutes program (CFDA 15.805). The purpose of the award is to determine the effects of per- and polyfluoroalkyl substances (PFAS) on microbiome health and neurotoxicity in bluegill, an economically and ecologically important fish species in the Great Lakes region. The key research activities include: 1) characterizing PFAS bioaccumulation and...
- This Project Grant award from the National Science Foundation (CFDA 47.041, Engineering) provides $280,000 to Temple University-Of The Commonwealth System Of Higher Education for a collaborative research project focused on mitigating antibiotic resistance. The key objectives are to: Understand the interactions between antibiotic resistance genes and carbon nanomaterials using reduced graphene oxide membranes; Enhance the electrostatic adsorption of antibiotic resistance genes on the modified...
- The University of Maryland, College Park was awarded a $1,345,283 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to create a community-driven Water Emergency Team (WET) to evaluate antibiotic-resistant bacteria exposures and household health risks from sewer overflows and basement flooding in Baltimore, Maryland. The key objectives of the project are to: 1) develop a rapid-response WET in collaboration with community organizations to...
- This $388,362 Project Grant awarded by the Environmental Protection Agency (EPA) Region 4 under the Geographic Programs - South Florida Geographic Initiatives Program (CFDA 66.484) will fund the University of Miami's Rosenstiel School of Marine and Atmospheric Science (RSMAS) to characterize nutrient and microbial water quality in the nearshore "halo zone" of the Florida Keys and its connections to the broader regional water quality of the reef tract. Key activities include...
- The National Science Foundation (NSF) awarded a $650,000 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to the University of South Florida (USF) to develop innovative decentralized wastewater management technologies and strategies for U.S. Pacific islands. The project, titled "Towards Resilient, Equitable, Safe and Sustainable Water for Islands (RESSI-H2O)", assembles a multi-disciplinary team from USF, the University of Hawai'i at Mānoa,...
- This Project Grant award of $410,977 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to Case Western Reserve University (CWRU) will fund research to develop methods for designing effective bacteriophage cocktails to precisely control the growth of unwanted bacteria in water systems. The key objectives are to: Identify genetic and transcriptomic markers of synergistic and antagonistic interactions between bacteriophages to guide the rational design of safe and...
- This $1,000,000 project grant from the Environmental Protection Agency Office for Water under the Section 104(b)(3) Surveys, Studies, Investigations, Demonstrations, and Training Grants and Cooperative Agreements program (CFDA 66.436) supports the Environmental Finance Center Network in increasing the technical, managerial, and financial capacity of small wastewater systems and onsite/decentralized wastewater systems. The University of New Mexico serves as the lead awardee coordinating seven...
DESCRIPTION:THE PURPOSE OF THIS PROJECT IS TO QUANTIFY THE EFFECTIVENESS OF WASTEWATER TREATMENT ON THE REMOVAL AND/OR SELECTION OF ANTIMICROBIAL RESISTANT BACTERIA AND GENES. THE PROJECT WILL EVALUATE THE PROCESS FOR REMOVING ANTIMICROBIAL RESISTANT BACTERIA AND GENES THROUGHOUT THE WASTEWATER TREATMENT TRAIN INCLUDING MEASURING CONCENTRATIONS/LOADS ENTERING AND BEING DISCHARGED FROM WASTEWATER TREATMENT. THE PROJECT WILL PROVIDE AN UNDERSTANDING OF THE FATE AND TRANSPORT OF ANTIMICROBIAL RESISTANT BACTERIA AND GENES IN EFFLUENT DISCHARGE BY MONITORING A RIVER THAT IS SET TO RECEIVE WASTEWATER TREATMENT PLANT DISCHARGE FOR THE FIRST TIME. A KEY FOCUS OF THE PROJECT IS ON THE CLINICAL RELEVANCE OF RESISTANT GENES AND BACTERIA THAT ARE DISCHARGED FROM THE TREATMENT PROCESS SO THAT RISKS CAN BE PUT INTO PERSPECTIVE WITH OTHER INDUSTRIAL AND AGRICULTURAL SECTORS CONNECTED TO ANTIMICROBIAL RESISTANCE (AMR).ACTIVITIES:ACTIVITIES TO ACHIEVE PROJECT OBJECTIVES INCLUDE BREAKING DOWN THE WASTEWATER TREATMENT PROCESS INTO UNIT OPERATIONS AND DETERMINING CHANGES IN AMR QUANTITIES AMONG SYSTEM COMPONENTS AND IN RELATION TO TREATMENT FACILITY OPERATIONAL PARAMETERS. RESEARCH FRAMEWORK WILL INTEGRATE ANTIMICROBIAL RESISTANCE GENE AND RESISTANT BACTERIA QUANTIFICATION AND GENOMIC AND METAGENOMIC-BASED DNA SEQUENCING TO DETERMINE AMR MASS BALANCES AND CHANGES IN CLINICALLY RELEVANT GENOTYPES FROM TREATMENT FACILITY INFLUENT THROUGH THE TREATMENT TRAIN AND ULTIMATELY TO FACILITY OUTFLOWS. SUBRECIPIENT:THE PROJECT TEAM PLANS TO COLLABORATE WITH FLORIDA GULF COAST UNIVERSITY ($19,882) AND WASHINGTON STATE UNIVERSITY ($29,197+ COST SHARE OF $7,837 FOR THE TOTAL OF $37,034) FOR WASTEWATER TREATMENT SAMPLE COLLECTION. THE TEAM ADDITIONALLY PLAN TO COLLABORATE WITH MARQUETTE UNIVERSITY ($288,872 + COST SHARE OF $72,221 FOR THE TOTAL OF $361,093) FOR ADDITIONAL WASTEWATER TREATMENT SAMPLE COLLECTION AND MASS BALANCE CALCULATIONS THROUGH UNIT OPERATIONS. OUTCOMES:KEY OUTPUTS INCLUDE ANNUAL AND FINAL TECHNICAL REPORTS, PUBLICATIONS, AS WELL AS 1) INFORMATION ON THE TEMPORAL DYNAMICS OF AMR INTO TWO WASTEWATER TREATMENT PLANTS USING HISTORICAL DATA OVER A TEN-YEAR PERIOD TO UNDERSTAND HOW INFLUENT LOADS HAVE CHANGED OVER TIME, 2) NEW INFORMATION ON WHAT UNIT OPERATIONS ARE MOST SUCCESSFUL IN REMOVING AMR, AND 3)NEW INFORMATION ON THE IMPACT OF TREATMENT PLANT DISCHARGE INTO SURFACE WATERS. INTENDED BENEFICIARIES INCLUDE STATE AND LOCAL REGULATORS, WASTEWATER UTILITIES, WATER QUALITY PROGRAM MANAGERS AND THE COMMUNITIES SERVED BY PUBLIC WATER SYSTEMS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 4/23/25 | ||
| Not listed | $2.0m | 7/31/24 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
253405670S | Marquette University | Project Grant 84082701 | $288.9k | 12/13/24 |