Project Grant 2442755

Award Date 6/1/25
Completion Date 5/31/30
Dollars Obligated $411K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Cleveland, OH 44106, USA
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This federal Project Grant award, funded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), aims to develop methods for designing safe and effective bacteriophage cocktails to precisely control microbial growth in water systems. The $410,977 award to Case Western Reserve University (CWRU) will span 5 years, from June 1, 2025 to May 31, 2030.

The key objectives are to: (1) Identify genetic and transcriptomic markers of synergistic versus antagonistic bacteriophage cocktail interactions, and (2) Assess off-target infection risks using experimental and computational approaches. The research will provide a systematic understanding of the features of safe and effective bacteriophage cocktails, reducing the costs of unwanted microbial growth and better protecting public health in drinking water systems. The project also includes educational initiatives to train high school, undergraduate, and graduate students in bacteriophage biocontrol technologies.

Generated 4/29/25, 4:54 AM