Project Grant 2628626
- Federal Project Grant Award Summary Michigan State University received $325,937 in funding from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) for a collaborative research project running from September 1, 2025, through August 31, 2028. The award supports fundamental research investigating the structural and metabolic dynamics of bacterial microcompartments (BMCs)—protein-bounded cellular compartments found...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $427,615 to the Regents of the University of Michigan (effective August 1, 2026, through July 31, 2029) under the Biological Sciences program (CFDA 47.074) to support collaborative research on epigenetic silencing mechanisms. The primary deliverable is fundamental scientific research investigating how intrinsically disordered regions (IDRs) of proteins regulate the...
- Federal Project Grant Award Summary The National Science Foundation (NSF) awarded $195,526 to the Regents of the University of Minnesota under the Biological Sciences program (CFDA 47.074) for research addressing reproducibility challenges in cell-free protein synthesis systems. The project, initiated September 1, 2026, with completion targeted for August 31, 2027, will develop a comprehensive benchmarking framework and minimal information reporting standard for Protein Expression using...
- Federal Project Grant Award Summary The University of Michigan received a $449,996 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041) effective July 1, 2026 through June 30, 2029. The award funds research to understand the role of nuclear speckles in muscle stem cells through combined application of cellular engineering, biomaterials, bioinformatics, and genomic assays. The research will investigate...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $862,279 to the University of Michigan (Regents of the University of Michigan) under the Biological Sciences program (CFDA 47.074) to support research on RNA-RNA interactions regulating virulence gene expression in Listeria monocytogenes. The three-year project, initiated June 1, 2026 and completing May 31, 2029, will investigate how two noncoding RNAs in this...
- Federal Grant Award Summary Michigan State University received a $633,240 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective August 1, 2025, through July 31, 2029. This award supports the development of novel 1H-detected solid-state nuclear magnetic resonance (NMR) methodologies to characterize complex carbohydrate biopolymers in their native cellular environments. The research...
- Federal Grant Award Summary The University of Michigan received a $400,000 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective September 1, 2025 through August 31, 2028. This collaborative research project delivers fundamental scientific knowledge and experimental/theoretical models investigating the mechanics of tissue boundary formation during embryonic development. The primary...
- Federal Grant Award Summary The University of Michigan's Regents, through its Office of Research and Sponsored Projects Division, received a $370,000 Project Grant from the National Science Foundation's Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049) to develop advanced computational tools for simulating and optimizing the locomotion of microscopic particles in fluid environments. The project, awarded August 15, 2025, with completion...
- Federal Grant Award Summary The University of Michigan received a $220,000 Project Grant from the National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) under the Faculty Early Career Development (CAREER) program, awarded December 15, 2025, with completion targeted for December 31, 2027. The funded research will develop innovative approaches to engineer instructive microenvironments (niches) that guide individual stem cells toward precise regeneration of damaged tissues. The...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $692,207 Project Grant to the University of Florida (effective May 15, 2026, through April 30, 2029) under the Biological Sciences program (CFDA 47.074). The project develops recombinant globular protein vesicles (GPVs) with controlled membrane asymmetry and integrated signal transduction capabilities. The primary deliverables include engineered bolaamphiphilic fusion...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded $346,497 to the University of Michigan (Regents of the University of Michigan) on July 15, 2026, for a collaborative U.S.-United Kingdom research initiative focused on engineering novel protein-based synthetic cells. The project, which operates through June 30, 2029, will develop programmable, cell-sized protein structures derived from bacterial carboxysome building blocks that emulate critical features of living cells, including compartmentalization, selective permeability, and biochemical reaction organization. Using bottom-up and cell-free engineering approaches, the research team will investigate how carboxysome proteins can be assembled into synthetic cellular systems through four integrated research objectives, with particular emphasis on generating phase-separated carboxysome cargo condensates containing carbon-fixing enzymes. The project deliverables will advance the emerging field of engineering biology and synthetic biotechnology through development of new design principles, tools, and methodologies applicable to synthetic biology, biomanufacturing, agricultural biotechnology, and energy applications. The award supports workforce development through undergraduate, graduate, and postdoctoral training programs, while public engagement will be facilitated through educational programs and exhibits on biomanufacturing and synthetic biology. Additionally, the research is expected to generate outcomes in advanced protein-based biomaterials with applications across multiple biotechnology domains, directly supporting NSF's priorities in biotechnology and advanced manufacturing.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $346.5k | 7/9/26 |