Project Grant 2626041
- This National Science Foundation (NSF) Project Grant, under the Biological Sciences program (CFDA 47.074), provides $240,000 in funding from February 1, 2024 to January 31, 2027 to support a postdoctoral research fellowship focused on investigating a novel circadian time-keeping mechanism revealed by environmental manipulation. The research plan aims to identify the location in the brain and the mechanism of a non-canonical clock that can rescue daily rhythms in mice with disrupted central clock...
- The National Institute of Neurological Disorders and Stroke awarded the University of Massachusetts Medical School $460,625 on August 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate time-dependent membrane proteomics in circadian pacemaker neurons. The recipient will use cutting-edge proteomic approaches combined with biotin proximity labeling to survey the membrane proteome of circadian neurons during the...
- The National Institute of General Medical Sciences awarded The Trustees of The University of Pennsylvania $487,287 on March 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support investigation of circadian rhythm mechanisms beyond traditional genetic control. The research explores how cells and organisms maintain daily temporal organization through integration of genetic and non-genetic mechanisms, with focus on metabolic and redox processes that sustain...
- The National Institute of General Medical Sciences awarded California Institute of Technology $1.872 million on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on mechanisms in the mammalian circadian clock. The research addresses gaps in understanding the central transcription-translation feedback loop (TTFL) that drives circadian oscillations, which regulate sleep-wake patterns, metabolism, and immune responses. The work comprises...
- The National Institute of General Medical Sciences awarded the University of Cincinnati $760,178 on September 10, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate molecular mechanisms that determine circadian rhythm period and light-dependent phase shift. The recipient will combine mathematical modeling, statistical uncertainty quantification methods, and experimental validation to elucidate how transcriptional and translational feedback loops...
- The National Institute of Neurological Disorders and Stroke awarded Boston Children's Hospital $711,952 under Project Grant R01NS144151 on May 2, 2026, to investigate circadian regulation of synaptic function and sleep-wake behavior. The research examines how circadian rhythms regulate synaptic function to modulate behavior with time of day, focusing on the molecular mechanisms by which the transcription factor BMAL1 and its phosphorylation at serine 42 orchestrate synaptic vesicle dynamics,...
- The National Institute of Neurological Disorders and Stroke awarded The Ohio State University $630,925 on May 1, 2026, to investigate circadian clock physiology in cortico-limbic brain circuits and its role in regulating complex behavioral states including mood, memory, and executive function. The research examines how transcriptional timing feedback loops and clock oscillators outside the suprachiasmatic nucleus operate at cellular and systems levels within cortico-limbic circuits, and how...
- The National Institute of Neurological Disorders and Stroke awarded the University of California, Los Angeles $433,125 on September 2, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate genes and neurons associated with circadian chronotype across Drosophila species. The project quantifies locomotor activity patterns across 63 related Drosophilid species to identify genetic and neural correlates of morning and evening...
- The National Institute of General Medical Sciences awarded Vanderbilt University $648,480 on June 12, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on the mechanism and evolution of circadian clocks and photoperiodism. The award funds basic research examining post-translational molecular mechanisms of circadian clocks in bacterial and mammalian model systems. Work will address how biochemical mechanisms sustain long-period (~24 hour)...
- The National Heart Lung and Blood Institute awarded Emory University $248,705 on February 2, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate relationships between naturalistic light exposure and sleep regularity. The project examines how dimensions of light exposure impact sleep regularity and identifies biological markers of sleep regularity, with investigation of moderation by factors such as age and sex. The research develops and validates findings...
CONFERENCE: SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 2026 - TIME MATTERS: BIOLOGICAL RHYTHMS SHAPING LIFE AND HEALTH -BIOLOGICAL RHYTHMS PERMEATE ALL ASPECTS OF LIFE, REGULATING EVERYTHING FROM SINGLE GENES TO ENTIRE ECOSYSTEMS. THE UBIQUITOUS IMPORTANCE OF BIOLOGICAL RHYTHMS MAKES TIMEKEEPING ONE OF THE FUNDAMENTAL ?RULES OF LIFE? ON OUR PLANET, THAT CAN POSITIVELY OR NEGATIVELY AFFECT SOCIETY IN CRITICAL WAYS. GIVEN THE VITAL ROLE OF BIOLOGICAL RHYTHMS, THE STUDY OF CHRONOBIOLOGY IS ESSENTIAL TO ALL MAJOR QUESTIONS IN BIOLOGY. THE LARGEST SOCIETY OF SCIENTISTS INVOLVED IN THE QUEST FOR KNOWLEDGE IN THIS AREA IS THE SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS (SRBR), WHOSE PRIMARY MISSION IS TO CONNECT RESEARCHERS IN THE RHYTHMS FIELD AND DISSEMINATE RESEARCH TO THE PUBLIC. TO FULFILL THIS ROLE, SRBR HOSTS A BIANNUAL MEETING, WHERE ITS MEMBERS GATHER TO LEARN ABOUT THE MOST NOVEL AND EXCITING RESEARCH. THE UPCOMING ITERATION OF THIS MEETING, SRBR 2026: TIME MATTERS: BIOLOGICAL RHYTHMS SHAPING LIFE AND HEALTH, AIMS TO CAPITALIZE ON AN INFLUX OF RESEARCHERS JOINING THE FIELD, PROVIDING AN OPPORTUNITY TO INTEGRATE NEW DISCIPLINES INTO ESTABLISHED PARADIGMS AND EDUCATE TRAINEES ON HOW TO ASK USEFUL QUESTIONS WHILE CONDUCTING RHYTHMS RESEARCH. THIS PROJECT WILL ADVANCE THE FIELD AND PRODUCE POSITIVE BENEFITS IN SEVERAL WAYS. NOTABLY, SRBR WIDELY DISSEMINATES THE MOST RECENT RESEARCH IN THE FIELD OF CHRONOBIOLOGY VIA SEMINARS, WORKSHOPS, SOCIAL MEDIA, ETC., REACHING EVERYONE FROM RESEARCHERS TO MEMBERS OF THE PUBLIC. FURTHER, THE CONFLUENCE OF SO MANY EXPERIENCED RESEARCHERS AT SRBR 2026 OFFERS THE OPPORTUNITY TO ADVANCE THE TRAINING OF THE JUNIOR MEMBERS OF THE CHRONOBIOLOGY FIELD. IN THESE WAYS, THIS PROJECT WILL SUPPORT SRBR?S EFFORTS AT ADVANCING KNOWLEDGE, SUPPORTING EDUCATION, AND SERVING SOCIETY AT LARGE. THIS PROJECT ADVANCES NSF?S PRIORITIES IN BIOTECHNOLOGY AND ARTIFICIAL INTELLIGENCE. THE SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS (SRBR) WAS ESTABLISHED TO ENHANCE AND ADVOCATE FOR CHRONOBIOLOGICAL RESEARCH, A MISSION WHICH IS IMPART FULFILLED VIA ITS BIANNUAL CONFERENCE. WITH THE BREADTH OF RESEARCH PRESENTED AT SRBR 2026, SUPPORT FOR THE TRAINING ASPECTS OF THIS MEETING PRESENTS TWO PRIMARY BROADER IMPACTS. FIRST, SRBR 2026 WIDELY DISSEMINATES THE MOST RECENT RESEARCH IN THE FIELD OF CHRONOBIOLOGY. SECOND, THE CONFLUENCE OF SO MANY EXPERIENCED RESEARCHERS WILL ADVANCE THE TRAINING OF THE JUNIOR MEMBERS OF THE CHRONOBIOLOGY. THIS PROJECT WILL SUPPORT JUNIOR RESEARCHERS IN OUR FIELD BY FACILITATING OUR EFFORTS TO HOST 1) THE SRBR 2026 TRAINEE AND PROFESSIONAL DEVELOPMENT DAY AND JUNIOR FACULTY WORKSHOPS ON-SITE ON THE DAY BEFORE THE CONFERENCE STARTS, 2) A PRE-CONFERENCE VIRTUAL MENTORING EVENT, 3) TRAINEE DEVELOPMENT EVENTS DURING THE CONFERENCE ITSELF, AND 4) NETWORKING EVENTS THAT WILL ALLOW FIRST TIME STUDENTS TO NOT ONLY INTERACT WITH THEIR PEERS, BUT TO INTERFACE WITH SENIOR RESEARCHERS IN THE FIELD. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $20.0k | 7/17/26 |