Project Grant 2622393
- This $240,000 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will fund a postdoctoral research fellowship to investigate the role of amphibian skin microbiomes in limiting the growth of deadly fungal pathogens. The research aims to explore the mechanisms by which certain skin microbes inhibit the fungal agents responsible for amphibian population declines, and to pilot the use of "antifungal probiotics" to protect...
- The National Science Foundation Division of Integrative Organismal Systems awarded a $276,018 Project Grant to The George Washington University from January 15, 2022 to December 31, 2024. The grant supports collaborative research between U.S. and U.K. researchers on "The Amphibian Skin Microbial-Immune Interface and Its Impact on Infection Outcome." This project aligns with the NSF Biological Sciences program (CFDA 47.074), which aims to advance the fundamental understanding of...
- This $945,365 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research on how habitat disruptions and fragmentation influence the skin microbiomes of amphibians and their ability to resist fungal infections. The primary objectives are to: 1) experimentally test the "adaptive microbiome principle" by exposing amphibians to varying microbial environments and fungal pathogens in controlled lab conditions, and 2)...
- This $1,353,246 project grant from the National Science Foundation Division of Integrative Organismal Systems will fund research into the role of macrophages in amphibian skin antifungal defenses against the deadly chytrid fungus Batrachochytrium dendrobatidis (Bd) at Vanderbilt University Medical Center from August 1, 2022 to July 31, 2025. The research aims to define the interactions between frog macrophage subsets and Bd, examine the effects of Bd on interactions between frog macrophages...
- The National Science Foundation awarded The Pennsylvania State University a $116,657 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to investigate the relationship between deforestation and amphibian microbiomes and the role this plays in disease emergence. The research will examine how habitat fragmentation impacts pathogen exposure rates and the establishment of "microbiome memory" in amphibians, altering disease risk. Field experiments using...
- This $355,123 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research to genetically modify the immune system of the African clawed frog (Xenopus tropicalis) to improve its resistance to the deadly chytrid fungus. The goal is to identify how altering the frog's major histocompatibility complex (MHC) genes affects its ability to fight off this pathogen and survive infection. The project includes a sub-award to the University...
- This National Science Foundation (NSF) Project Grant award of $240,000, funded under the Biological Sciences program (CFDA 47.074), will support a 3-year postdoctoral research fellowship to investigate the history and evolution of the amphibian pathogen Batrachochytrium dendrobatidis (BD). The research aims to: Develop new genetic tools to selectively sequence DNA from BD and its amphibian hosts, even in highly contaminated and fragmented samples. Use these new genetic tools to genotype BD...
- The National Science Foundation (NSF) awarded a $494,261 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on frog skin evolution and adaptations. The project aims to: 1) quantify how frog skin has evolved over the past 200 million years in response to abiotic and biotic factors, 2) experimentally test the ability of anuran skin to decouple respiration and water loss, and 3) incorporate...
- Federal Project Grant Award Summary Gettysburg College received a $233,022 Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074) for research on disease transmission dynamics in tropical frog communities. The award, which commenced March 1, 2026 and concludes February 28, 2029, supports an integrated investigation into how the sensory-driven foraging behavior of disease vectors—specifically fly-vectors...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Biological Infrastructure awarded a $270,000 Postdoctoral Research Fellowship through the Biological Sciences program (CFDA 47.074) on July 1, 2025, with completion scheduled for June 30, 2028. This fellowship supports research investigating how pathogen-host genomic interactions influence the success of species invasions, using wild rodent populations in New England as a primary research model. The fellow will...
The National Science Foundation (NSF) awarded George Washington University a $1.199 million Project Grant under the Biological Sciences program (CFDA 47.074), effective August 1, 2026 through July 31, 2030. This research initiative investigates the interactions between amphibian skin microbiomes and immune systems to understand mechanisms of resistance to fungal infections, particularly those caused by Batrachochytrium dendrobatidis (Bd), a pathogen responsible for significant amphibian population declines globally. Using frogs as a model system, the project will examine how beneficial skin microbes and immune defenses collaborate to maintain health, identify where this partnership fails during fungal infection, and elucidate why resistance varies across species. Beyond advancing fundamental understanding of host-microbe interactions, the grant supports the development of potential disease-control strategies applicable to wildlife conservation and agricultural and human health contexts through microbiome engineering and immune system manipulation. The award incorporates workforce development components, providing training for students and early-career researchers in interdisciplinary methods spanning immunology, microbiology, and computational biology. The project also includes broader impacts through engagement with conservation practitioners, museums, and public education initiatives, directly supporting NSF's biotechnology priorities and addressing the rising global threat of invasive fungal diseases to biodiversity and human welfare.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 6/16/26 |