Project Grant 2611174
- Federal Project Grant Award Summary Brown University received a $1.337 million Project Grant from the National Science Foundation (NSF) Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074) effective September 1, 2025, through August 31, 2029. The award supports fundamental research investigating the evolutionary introduction of asymmetric cell division in regulative embryos, utilizing echinoderms—specifically sea urchins and sea stars—as model organisms. The primary...
- Federal Project Grant Award Summary Brown University received a $229,691 Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074) effective May 1, 2026 through April 30, 2031. This collaborative long-term research award supports experimental investigation of trophic dynamics and energy flows in semiarid ecosystems, leveraging more than 37 years of continuous field research. The project will generate...
- Federal Project Grant Award Summary Brown University received a $1.12 million Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) on September 15, 2026, with a completion date of August 31, 2029. This collaborative research initiative delivers experimental and analytical products characterizing bird flight performance under turbulent atmospheric conditions. The core deliverables...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.3 million to the University of Pennsylvania under the Biological Sciences program (CFDA 47.074) for the project "Dissecting the HIRA/HIR Chaperone Complex in the Chromatin Landscape." The award, effective July 1, 2026 through June 30, 2029, funds fundamental research into the structural and biochemical mechanisms of the HIRA/HIR (histone regulatory A/histone...
- Federal Project Grant Award Summary Brown University received a $1,012,160 Project Grant award from the National Science Foundation (NSF) Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, through August 31, 2029. The award supports the development of novel computational tools and frameworks that integrate molecular and structural imaging data to create comprehensive three-dimensional maps of brain organization. Specifically,...
- This federal Project Grant award, valued at $541,574.00 and awarded on January 15, 2025, is funded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) Federal Grant Program. The project, titled "COLLABORATIVE RESEARCH: NSF/MCB-BSF: THE EFFECT OF TRANSCRIPTION FACTOR BINDING ON UV LESION ACCUMULATION", aims to determine whether transcription factor binding to DNA makes it more susceptible to damage or impedes DNA repair, leading to increased genomic...
- Federal Project Grant Award Summary Brown University received a $250,000 Project Grant award from the National Science Foundation's Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049), effective August 1, 2025, through July 31, 2029. This collaborative research initiative addresses privacy and fairness challenges in advanced genomic research by developing federated learning methodologies. The project focuses on enabling secure integration of...
- Federal Project Grant Award Summary MIT received $1,041,774 in funding from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) for a collaborative research project running from August 1, 2025, through July 31, 2029. This project grant supports fundamental research investigating analog information storage in chromatin states, with the goal of understanding how cells encode and maintain their identity through...
- Federal Grant Award Summary Brown University received a $116,000 Project Grant award from the National Science Foundation's Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, through August 31, 2028. This collaborative research project investigates bone mechanoadaptation in Peromyscus (deer mice) species to elucidate whether limb bone structure is primarily determined by genetic inheritance or developmental responses to...
- Federal Grant Award Summary The Johns Hopkins University received a $1,199,593 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), awarded September 1, 2025, with a completion date of August 31, 2029. This grant supports fundamental research to advance understanding of nucleosome mobility and chromatin dynamics through single-molecule manipulation techniques. The project will develop and apply...
Brown University received a $1.2 million Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), awarded July 1, 2026, with completion expected by June 30, 2030. The research investigates the fundamental mechanisms of base excision repair (BER) within nucleosomes—the primary structural units of chromatin—to advance understanding of how DNA repair enzymes function when genomic DNA is packaged into higher-order chromatin structures. Using chemical, biochemical, biophysical, and molecular biology approaches, the project will characterize how chromatin architectural proteins and chromatin composition regulate BER efficiency and enzyme access to damaged DNA, thereby advancing national interests in health, biotechnology, and scientific innovation. The award deliverables include peer-reviewed research publications and scientific findings that define how chromatin features influence genome maintenance mechanisms. The project also commits to workforce development and public engagement through mentoring and training of graduate student researchers in protein and DNA chemistry, biophysics, and molecular biology, along with sustained outreach activities including tutoring and annual STEM engagement events for elementary, middle, and high school students. These complementary activities strengthen the competitive STEM workforce pipeline while broadening participation in science and enhancing public understanding of cellular mechanisms for preserving genetic information.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 6/17/26 |