Project Grant 2607478
- Federal Project Grant Award Summary The University of Delaware received a $300,000 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (Engineering program, CFDA 47.041) effective September 1, 2025, through August 31, 2027, to develop synthetic biology tools for controlling macrophage immune cell phenotype through histone lactylation modulation. The primary deliverables include precision engineering tools—lactylation...
- Federal Grant Award Summary The University of Delaware received a $500,000 Project Grant from the National Science Foundation's Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective August 1, 2026 through July 31, 2029. This collaborative research award supports the development of innovative biotechnology tools for targeted proximity labeling of extracellular vesicles (EVs)—membrane-bound particles released by cellular organisms that carry...
- Federal Grant Award Summary The University of Delaware received a $1.0 million Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective July 1, 2026 through June 30, 2029. This research initiative, titled "Tools4Cells: Multi-Kingdom Acetyl-CoA Sensing for Real-Time Reporting and Control of Metabolism," develops protein-based biosensor technology to enable real-time monitoring of...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation (CMMI) awarded $298,403 to the New Jersey Institute of Technology on September 1, 2026, for collaborative research on predictive modeling of coupled nanoparticle-membrane mechanics as determinants of endocytic pathways. The project, which extends through August 31, 2029, will deliver a predictive framework for understanding how nanogel deformability and cellular...
- Federal Project Grant Award Summary The University of Delaware received a $167,000 Project Grant award dated August 1, 2025, from the National Science Foundation (NSF) Division of Computer and Network Systems under the Computer and Information Science and Engineering program (CFDA 47.070). This collaborative research initiative will develop a multi-level control architecture for powered robotic ankle-foot prostheses designed to enhance mobility over challenging and uneven terrains. The project...
- Federal Project Grant Summary The University of Delaware received a $392,495 Project Grant award dated July 1, 2026, from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports fundamental research into the mechanisms of extracellular vesicle (EV) biogenesis and uptake through February 28, 2031. The project delivers research findings and novel methodological tools that advance understanding of how...
- Federal Grant Award Summary The University of Delaware received a $186,024 Project Grant award from the National Science Foundation's Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, through August 31, 2028. This collaborative research initiative addresses fundamental questions about how mechanical forces in plant tissues enable growth while maintaining cell-to-cell connectivity. The project delivers integrated research outputs...
- Federal Project Grant Award Summary The University of Delaware received a $400,000 project grant from the National Science Foundation (NSF) Division of Computing and Communication Foundations under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), effective June 1, 2025 through May 31, 2029. This award supports the development of advanced software verification tools designed to help scientific software developers identify and eliminate defects in their code....
- Federal Grant Award Summary The University of Delaware received a $207,611 Project Grant award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041 – Engineering program) effective April 1, 2025, through March 31, 2028. This collaborative research project, conducted in partnership with the University of Colorado at Boulder, aims to develop advanced ankle-foot orthoses (AFOs) with customized and biomimetic stiffness...
- Federal Project Grant Award Summary The University of Delaware received a $430,675 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 15, 2025, with completion targeted for August 31, 2030. The award funds the Corbin Lab's research initiative titled "Probing Spatiotemporal Mechanobiology Through Novel Dynamic Material Platforms," which focuses on developing engineered...
The University of Delaware received a $279,964 Project Grant from the National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) effective September 1, 2026 through August 31, 2029. This collaborative research award supports the development of predictive computational models that characterize how the mechanical properties of soft nanoparticles interact with cell membrane mechanics to determine cellular uptake pathways. The primary deliverable is a mechanics-guided predictive framework that integrates multiscale computational modeling to establish relationships between nanogel deformability, cell mechanotype, and intracellular routing efficiency—knowledge intended to improve the rational design of safer and more effective nanoparticle-based drug delivery systems for cancer, fibrosis, inflammation, and other disease treatments. Beyond research outcomes, the award supports educational and workforce development activities, including training of graduate and undergraduate students in computational modeling, biomaterials, cell biology, and biomechanics. The project also includes outreach activities designed to introduce high school students to engineering and biomedical research. The work advances NSF's Engineering program objectives of fostering innovation and excellence in engineering research while contributing to national priorities in biotechnology, health, and scientific discovery.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $280.0k | 6/29/26 |