Project Grant 2603280
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $427,615 to the Regents of the University of Michigan (effective August 1, 2026, through July 31, 2029) under the Biological Sciences program (CFDA 47.074) to support collaborative research on epigenetic silencing mechanisms. The primary deliverable is fundamental scientific research investigating how intrinsically disordered regions (IDRs) of proteins regulate the...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.3 million to the University of Pennsylvania under the Biological Sciences program (CFDA 47.074) for the project "Dissecting the HIRA/HIR Chaperone Complex in the Chromatin Landscape." The award, effective July 1, 2026 through June 30, 2029, funds fundamental research into the structural and biochemical mechanisms of the HIRA/HIR (histone regulatory A/histone...
- Federal Project Grant Award Summary MIT received $1,041,774 in funding from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) for a collaborative research project running from August 1, 2025, through July 31, 2029. This project grant supports fundamental research investigating analog information storage in chromatin states, with the goal of understanding how cells encode and maintain their identity through...
- Federal Project Grant Award Summary Indiana University received a $1.0 million Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) effective August 1, 2025, through July 31, 2028. The award funds fundamental research investigating chromatin mechanisms and epigenetic regulation during cerebral cortex development in mammalian models. The research deliverables include scientific data,...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.2 million to the University of California, Davis under the Biological Sciences program (CFDA 47.074) on July 15, 2026, with a completion date of June 30, 2030. This Project Grant supports fundamental research into gene-specific nuclear messenger ribonucleoprotein (mRNP) assembly and quality control mechanisms. The research focuses on understanding how genetic...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $880,000 to the University of Massachusetts Lowell under the Biological Sciences program (CFDA 47.074) for a five-year CAREER grant (June 1, 2026 – May 31, 2031). The project investigates how transgenerational chromatin landscapes regulate cell fate and gene expression in Caenorhabditis elegans, focusing on the mechanisms of epigenetic inheritance—specifically, which histone...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $900,000 Project Grant to the University of Pennsylvania on September 15, 2025, with completion targeted for August 31, 2028. This collaborative research initiative, funded under the Biological Sciences program (CFDA 47.074), investigates the mechanism of transcription factor (TF) functional divergence through "differential usage of shared binding sites"...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $193,684 Project Grant to the University of Georgia Research Foundation effective September 1, 2025, through August 31, 2029, under the Biological Sciences program (CFDA 47.074). This collaborative research initiative investigates the mechanisms by which polo kinases maintain chiral asymmetry and support complex organizational patterning in Tetrahymena thermophila, a...
- Federal Project Grant Award Summary The J. David Gladstone Institutes received a $1.5M Project Grant award from the National Science Foundation's Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074), effective August 1, 2025 through July 31, 2028. The award supports fundamental research into the mechanisms of non-canonical retron phage defense systems in bacteria. Retrons are bacterial immune systems that detect phage infection and trigger infected cell death to...
- Federal Project Grant Award Summary The National Science Foundation (NSF), Division of Molecular and Cellular Biosciences, awarded $622,842 to the University of Pennsylvania on May 1, 2026, under the Biological Sciences program (CFDA 47.074) to support collaborative research on zygotic genome activation (ZGA) in fruit fly embryos. This project will deliver research outputs investigating how cells measure and respond to changes in the nuclear-to-cytoplasmic (N/C) ratio to control the timing of...
The National Science Foundation (NSF) awarded $1.5M to the Van Andel Research Institute under the Biological Sciences program (CFDA 47.074) to support fundamental research on epigenetic regulation and gene expression control. The four-year project, initiated July 1, 2026 and concluding June 30, 2030, will investigate how asymmetric histone and DNA modifications within individual nucleosomes coordinate to regulate developmental gene expression and cell type specification. The research will employ newly developed experimental tools to precisely manipulate the geometry of histone and DNA modifications, enabling systematic study of how distinct modification combinations influence gene regulation outcomes. This basic research will advance foundational knowledge in epigenetic regulation, developmental biology, and genome organization with potential applications in biotechnology and biomedicine. In addition to research deliverables, the project encompasses broader impacts through interdisciplinary education and outreach. The award will support training for graduate students and postdoctoral researchers in structural biology and epigenetics, engagement with high school biotechnology education programs, and public outreach activities designed to increase understanding of gene regulation mechanisms. The Division of Molecular and Cellular Biosciences, a major NSF funding component supporting 1,821 awards totaling $1.3B, administers this award to the non-profit research organization headquartered in Grand Rapids, Michigan.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 6/23/26 |