Project Grant 2555806
- The National Science Foundation Division of Chemistry awarded the University of Pennsylvania $600,000 on September 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to support research on cross-electrophile coupling methods for forming carbon-sulfur bonds led by Professor Patrick J. Walsh. The research develops transition metal-catalyzed processes to generate enantioenriched sulfur-based building blocks—compounds vital in organic synthesis and medicinal chemistry—from...
- The National Science Foundation Division of Chemistry awarded Massachusetts Institute of Technology $600,000 on August 15, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to conduct fundamental synthetic chemistry research on d-block and p-block element molecules, reagents, and precursors. Dr. Christopher C. Cummins and his research team will explore synthesis and characterization of strained, phosphorus-rich organic molecules, with particular focus on...
- The National Science Foundation Division of Chemistry awarded the University of Pennsylvania $463,725 on September 1, 2026, for a Research Experiences for Undergraduates (REU) Site program in novel techniques and applications in catalysis research and molecular dynamics, running through August 31, 2029. The program trains ten undergraduate students annually for ten-week summer research experiences during 2027–2029 at the University of Pennsylvania's Philadelphia campus. Participants undertake...
- The National Science Foundation Division of Chemistry awarded New York University $750,000 in funding on April 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) for research on synthetic strategies for polycyclic meroterpenoids and sulfur-containing macrolactam natural products. Dr. Martin Tomanik's research group will develop new chemical approaches to synthesize architecturally complex natural products—secondary metabolites produced by plants, fungi, and...
- The National Science Foundation Division of Chemistry awarded the University of Pennsylvania $497,504 on August 15, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to develop biotechnology platforms based on synthetic genetic polymers known as xeno nucleic acids (XNAs) for protein recognition and aggregation control. The research team will establish two complementary XNA-SELEX (in vitro evolution) platforms to identify functional XNAs capable of selectively interacting...
- This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
- Federal Grant Award Summary Under the Mathematical and Physical Sciences (CFDA 47.049) program administered by the National Science Foundation's Division of Chemistry, the University of Pennsylvania received a $600,000 Project Grant awarded September 1, 2025, with completion targeted for August 31, 2028. Principal Investigator Professor Neil C. Tomson's research team will deliver fundamental scientific knowledge and catalytic technologies focused on the selective activation and functionalization...
- The National Science Foundation Division of Chemistry awarded Rice University $650,000 on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to fund Professor David Sarlah's research on enabling strategies for synthesis of complex natural products. The award supports development of novel synthetic pathways and chemical reactions to simplify preparation and modification of bioactive natural product molecules with applications in pharmaceutical and agrochemical...
- The National Science Foundation Division of Chemistry awarded $525,000 to The Trustees of the University of Pennsylvania through the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support synthetic studies on herquline and lycopodium alkaloids from August 1, 2022 to July 31, 2025. Under this Project Grant, Professor Dirk Trauner of the University of Pennsylvania will develop new organoboron chemistry methods to synthesize the natural product herquline A, which has...
- The National Science Foundation Division of Chemistry awarded The Pennsylvania State University $250,662 on August 15, 2026, under the Mathematical and Physical Sciences program to support fundamental research on olefin upgrading using dynamic shapeshifting ligands. Professor Jonathan L. Kuo's research group will develop catalytic methods to convert simple olefins (alkenes)—commodity chemicals derived from petroleum or biomass—into higher-value chemical products by constructing rearrangement...
The National Science Foundation Division of Chemistry awarded the University of Pennsylvania $650,000 on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to investigate biosynthetic pathways and establish new chemical synthesis methodology. Dr. Dirk Trauner will study how living organisms build complex molecules and apply those insights to develop efficient synthetic routes for biologically active compounds. The research focuses on biosynthetically inspired cationic cascade reactions involving unusual carbocations and interrupted Nazarov cyclizations, with mechanistic studies targeting the biosynthesis of structurally complex polyketides including varilactones and somalactams. The project will establish strategies for controlling highly reactive cationic intermediates and develop synthetic methodologies for complex molecular targets. Work is performed in Philadelphia, Pennsylvania, with a period of performance from August 1, 2026, through July 31, 2029. The award supports training of undergraduate students, graduate students, and postdoctoral researchers in modern chemical synthesis and will advance organic chemistry and biotechnology with potential applications in medicines, agricultural products, and other technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.0k | 7/31/26 |