Project Grant 2554753
- Federal Project Grant Award Summary The National Science Foundation's Division of Chemistry awarded Rice University $550,000 under the Mathematical and Physical Sciences (CFDA 47.049) program on June 15, 2025, to support Professor Hans Renata's research on chemoenzymatic total synthesis of complex terpenoid natural products through May 31, 2028. The research develops hybrid synthetic strategies combining enzymatic catalysis with modern organic chemistry methodologies to efficiently synthesize...
- Federal Grant Award Summary Rice University received a $400,000 project grant from the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049), effective September 1, 2025 through August 31, 2028. Under the direction of Professor László Kórti, the research project develops innovative synthetic chemistry reactions for constructing nitrogen-containing heterocycles by strategically cleaving weak nitrogen-oxygen (N-O) bonds to...
- The National Science Foundation Division of Chemistry awarded the University of Pennsylvania $650,000 on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to investigate biosynthetic pathways and establish new chemical synthesis methodology. Dr. Dirk Trauner will study how living organisms build complex molecules and apply those insights to develop efficient synthetic routes for biologically active compounds. The research focuses on biosynthetically inspired...
- Under a $530,000 National Science Foundation Project Grant awarded August 1, 2023 through the Mathematical and Physical Sciences program (CFDA 47.049), Professor Anatoly Kolomeisky of William Marsh Rice University and his research group will develop quantitative models and theoretical frameworks to understand the role of heterogeneity in chemical and biological processes. Through analytical models, numerical calculations, machine learning, and molecular dynamics simulations, the team will...
- The National Science Foundation Division of Chemistry awarded Rice University $204,888 on July 15, 2026, under the Research Experiences for Undergraduates (REU) Site program to operate a ten-week summer research program in chemical nanoscience for ten undergraduate students annually from 2027 through 2029 in Houston, Texas. The program, titled Research and Leadership Enabling Advanced Discoveries (RLEAD) in Chemical Nanoscience, places participants in collaborative research projects spanning...
- The National Institute of General Medical Sciences awarded William Marsh Rice University $410,184 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, Project Grant R35GM161793) to develop streamlined synthetic methods for the synthesis of N-unprotected chiral heterocycles and amines via organo- and transition metal catalysis over a five-year performance period through January 31, 2031. The research addresses limitations in current carbon-nitrogen...
- The National Science Foundation Division of Chemistry awarded Rice University $268,152 on August 1, 2026, for a CAREER project grant to develop multimetallic s-block clusters using earth-abundant metals for bond activation and chemical synthesis. Professor Samantha Yruegas will establish a synthetic framework for isolating and studying well-defined s-block metal clusters, specifically calcium and sodium compounds, using specialized molecular templates to guide assembly. The work addresses...
- The National Science Foundation Division of Chemistry awarded William Marsh Rice University a $475,000 Project Grant under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research titled "Harnessing the Power of Weak Bonds: Cleavage of N-O Bonds as Key Steps in Domino and Rearrangement Reactions of Functionalized Hydroxylamines" from May 1, 2021 to April 30, 2024. The grant will fund research at Rice University investigating the cleavage of...
- David Sarlah of the University of Illinois at Urbana-Champaign will utilize $514,006 in funding from the National Science Foundation's Mathematical and Physical Sciences program to support research in innovative strategies for the complex, total synthesis of naturally occurring molecules from May 1, 2022 to April 30, 2025. Specifically, Sarlah's project will identify novel disconnections and underutilized chemical processes to enable more rapid and controlled preparation of desired molecular...
- The National Science Foundation Division of Chemistry awarded $600,000 to The Regents of the University of Colorado on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to develop stereospecific methods for constructing sugar-based molecules. Dr. Maciej A. Walczak will lead research to create more reliable and predictable synthetic approaches for building complex carbohydrate structures with precise three-dimensional arrangements. The work targets applications in...
The National Science Foundation Division of Chemistry awarded Rice University $650,000 on August 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to fund Professor David Sarlah's research on enabling strategies for synthesis of complex natural products. The award supports development of novel synthetic pathways and chemical reactions to simplify preparation and modification of bioactive natural product molecules with applications in pharmaceutical and agrochemical manufacturing. Specific research focuses include stereoselective olefination chemistry to access the strained bicyclic system of cripowellins-based alkaloids, a labdane-to-clerodane skeletal rearrangement to open new pathways between terpenoid classes, and a regiodivergent transition metal-catalyzed cycloaddition strategy for cyclophane-containing peptides and other complex structures. The project integrates research training for undergraduate and graduate students with STEM outreach activities, including continuation of the Sarlah Laboratory's Science in Action program, which delivers hands-on science education in the Houston area. Work is performed at Rice University in Houston, Texas, with a period of performance from August 1, 2026, through July 31, 2029. This is a project grant, a form of assistance for a discrete, time-limited research effort led by the named investigator.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.0k | 7/31/26 |