Project Grant 2554677
- The National Science Foundation (NSF) awarded a $513,894 Project Grant under its Mathematical and Physical Sciences program (CFDA 47.049) to Tufts University. This 3-year grant, effective July 1, 2023, supports Professor Clay S. Bennett's research to develop new methods for synthesizing deoxy sugars - an important component of many biologically active natural products. The project aims to expand upon approaches that activate sugar hemiacetals as glycosyl sulfonates or tert-butyldimethylsilyl...
- Project Grant Award Summary The National Science Foundation's Division of Chemistry awarded $650,000 to the University of Oklahoma to support research on sulfur-mediated strategies for stereocontrolled glycosylation under the Mathematical and Physical Sciences program (CFDA 47.049). Beginning August 1, 2026, and concluding July 31, 2029, Dr. Indrajeet Sharma will develop sustainable synthetic chemistry methods for producing carbohydrate-based molecules critical to pharmaceuticals, vaccines,...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Chemistry awarded a $600,000 Project Grant to New York University under the Mathematical and Physical Sciences program (CFDA 47.049) effective August 1, 2025, with a completion date of July 31, 2028. Under the direction of Professor Diao, the research team will develop novel bidentate chiral nitrogen ligands—specifically imine-oxazoline (IMOX) and imine-imidazole (IMIM) compounds derived from amino acids—to...
- Federal Grant Award Summary Dr. Brewer at the University of Vermont & State Agricultural College is conducting fundamental research in synthetic organic chemistry under a $400,000 Project Grant from the National Science Foundation's Division of Chemistry (Mathematical and Physical Sciences program, CFDA 47.049). The award, effective September 1, 2025 through August 31, 2028, supports the development of novel synthetic methods to prepare encarbamates and nitrogen-containing compounds...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Chemistry awarded a Project Grant of $602,976 to Scripps Research Institute under the Mathematical and Physical Sciences program (CFDA 47.049) effective September 1, 2025, through August 31, 2028. Under the direction of Professor Donna G. Blackmond, the research initiative explores the emergence of homochiral biological polymers from chiral molecular building blocks, investigating how exclusively one mirror-image...
- Federal Grant Award Summary Under the Mathematical and Physical Sciences (CFDA 47.049) program administered by the National Science Foundation's Division of Chemistry, the University of Pennsylvania received a $600,000 Project Grant awarded September 1, 2025, with completion targeted for August 31, 2028. Principal Investigator Professor Neil C. Tomson's research team will deliver fundamental scientific knowledge and catalytic technologies focused on the selective activation and functionalization...
- Federal Grant Award Summary The National Science Foundation's Division of Chemistry awarded a $426,000 Project Grant (CFDA 47.049, Mathematical and Physical Sciences program) to the University of California, San Francisco effective September 1, 2025, through August 31, 2028. This collaborative research initiative, led by Professor William DeGrado at UCSF in partnership with Professors Michael Therien and David Beratan at Duke University, focuses on developing de novo protein constructs for...
- Federal Project Grant Award Summary The National Science Foundation's Division of Chemistry awarded Rice University $550,000 under the Mathematical and Physical Sciences (CFDA 47.049) program on June 15, 2025, to support Professor Hans Renata's research on chemoenzymatic total synthesis of complex terpenoid natural products through May 31, 2028. The research develops hybrid synthetic strategies combining enzymatic catalysis with modern organic chemistry methodologies to efficiently synthesize...
- Federal Project Grant Award Summary This $800,000 project grant, awarded September 1, 2025, through the National Science Foundation's Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049), supports fundamental research on collagen structure and function at Tufts University. Principal Investigator Dr. Joshua Kritzer and co-investigators Dr. James Baleja and Dr. Yu-Shan Lin will develop a novel stapling strategy using the artificial amino acid 4-mercaptoproline...
- Federal Grant Award Summary The National Science Foundation's Division of Chemistry has awarded the University of Utah $639,000 under the Mathematical and Physical Sciences program (CFDA 47.049) for the project "Chemical Toolkit for Monitoring and Modulating Receptor Tyrosine Phosphatase Activity." The award, initiated September 1, 2025, and extending through August 31, 2028, supports a collaborative research effort led by Professor Amy Barrios at the University of Utah and Professor...
The National Science Foundation (NSF) Division of Chemistry awarded Tufts University $586,353 under the Mathematical and Physical Sciences program (CFDA 47.049) to develop synthetic methods for deoxy sugar oligosaccharide glycopeptides—a class of molecules with potent biological activity and unprecedented chemical structures. Under the direction of Dr. Clay S. Bennett, the project, which runs from August 1, 2026, through July 31, 2029, will advance the first total synthesis of this compound class by establishing new chemical technologies and reaction methodologies. The research will focus on selective activation strategies for deoxy sugar hemiacetals, thioglycosides, and tert-butyldimethylsilyl glycosides to enable efficient oligosaccharide chain assembly with high selectivity. The project delivers both direct research outputs and broader workforce development outcomes. Core deliverables include novel synthetic procedures and mechanistic understanding of glycosylation reactions applicable to broader carbohydrate synthesis applications across pharmaceutical, chemical, and biotechnology sectors. The award also supports training in synthetic and bioorganic chemistry for undergraduate and graduate students and includes outreach activities to secondary education students to cultivate the next-generation biotechnology workforce. By advancing domestic synthetic capabilities for complex carbohydrates, this research contributes to technological innovation across agricultural, advanced manufacturing, chemical, and pharmaceutical industries.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $586.4k | 7/7/26 |