Project Grant 2548055
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $1.49M to The Regents of the University of Colorado (Boulder) under the Biological Sciences program (CFDA 47.074) on June 15, 2026, with completion scheduled for May 31, 2030. This collaborative research project focuses on elucidating the regulatory mechanisms of cyclin-dependent kinase 7 (CDK7) in controlling RNA polymerase II (RNAPII) transcription termination and RNA...
- Federal Project Grant Award Summary The University of Colorado received a $1.47M Project Grant from the National Science Foundation's Division of Environmental Biology (CFDA 47.074) effective September 1, 2025, through August 31, 2029. This collaborative research initiative investigates plant-mycorrhizal-soil interactions driving woody plant encroachment in alpine tundra ecosystems at the Niwot Ridge Long-Term Ecological Research (LTER) site in Boulder, Colorado. The primary deliverables include...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a collaborative research project grant of $171,000 to The Regents of the University of Colorado on June 15, 2026, under the Biological Sciences program (CFDA 47.074). The project, "Collaborative Research: Long-Range Signaling and Computation in Microtubules," will be executed through May 31, 2029. This project grant supports basic research investigating a...
- Federal Grant Award Summary The University of Colorado received a $100,000 Project Grant award from the National Science Foundation's Division of Mathematical Sciences under the Mathematical and Physical Sciences (CFDA 47.049) program, effective September 1, 2025, through August 31, 2028. This collaborative research initiative investigates multiscale flagellar dynamics in complex biological fluids, specifically examining how bacteria navigate viscoelastic environments such as mucus. The research...
- Federal Project Grant Award Summary The University of Colorado received a $824,293 Project Grant from the National Science Foundation's Division of Environmental Biology (CFDA 47.074 – Biological Sciences) awarded June 1, 2025, through May 31, 2028. This collaborative research initiative investigates the convergent evolution of inflated calyces and acylsugar chemical defenses in the Physalideae (tomatillo) tribe. The research will generate a comprehensive phylogenetic tree of all 310 species...
- Federal Project Grant Award Summary The University of Colorado received a $450,000 Project Grant from the National Science Foundation (NSF) Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049), awarded July 15, 2026, with completion targeted for June 30, 2029. The research focuses on developing pH-sensitive affinity molecules and multivalent therapeutic agents designed to enhance tumor penetration and retention for cancer treatment. The project...
- Federal Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded Colorado School of Mines $672,000 under the Biological Sciences program (CFDA 47.074) on June 1, 2026, with a completion date of May 31, 2031. This CAREER award funds development of a data-driven, multiscale computational framework designed to quantify pathway complexity during stochastic, out-of-equilibrium biomolecular assembly. The primary deliverable is an integrated...
- Federal Grant Award Summary The National Science Foundation (NSF) awarded a $250,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Colorado, effective July 1, 2026 through June 30, 2027. The project, "A Standard Enabled Synthetic Biology Workflow to Produce AI-Ready Data," addresses critical gaps in synthetic biology by developing standardized, machine-accessible experimental data and metadata workflows. The primary deliverables include...
- Federal Project Grant Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $478,840 to The Regents of the University of Colorado (University of Colorado-Denver) on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to support collaborative research on long-range signaling and computation in microtubules. The project, which runs through May 31, 2029, will deliver fundamental research integrating computational modeling with...
- Federal Project Grant Award Summary Colorado State University was awarded $420,762 under the National Science Foundation's Biological Sciences program (CFDA 47.074), Division of Environmental Biology, effective September 1, 2025, through August 31, 2029. This collaborative research project investigates the mechanisms driving woody plant encroachment into alpine tundra ecosystems by examining plant-mycorrhizal-soil interactions and their density-dependent feedback effects. The research integrates...
The University of Colorado, operating through its Office of Contracts and Grants Division in Boulder, Colorado, received a $1.058 million Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). Awarded July 1, 2026, with completion targeted for June 30, 2030, this grant supports fundamental research investigating the emergence of novel metabolic pathways through enzyme evolution and promiscuous enzyme activities. The project will deliver scientific research outcomes addressing how organisms develop new metabolic pathways by combining existing enzymes with side activities—termed promiscuous activities—into novel combinations. Using adaptive laboratory evolution coupled with genetic, omics, and biochemical approaches, the research will examine what promiscuous enzymes were available during pathway evolution, how mutations increase metabolic flux through emerging pathways, and why certain pathways evolve over alternatives. The work is expected to generate insights applicable to developing novel pathways for biodegradation and synthesis of pharmaceuticals, biofuels, and chemicals. The grant includes educational components providing training for undergraduate and graduate students and outreach to secondary school students, directly supporting NSF priorities in biotechnology, advanced materials, and manufacturing.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 6/26/26 |