Project Grant 2547489
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports a collaborative research project focused on studying the mechanics of tissue boundary formation. The $400,000 award, with a performance period from September 1, 2025 to August 31, 2028, will be used by researchers at the University of Michigan to investigate how mechanical forces inside the body help shape developing tissues during early stages of life. The project aims to combine...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) is supporting a collaborative research effort focused on developing an intelligent lab-on-chip device to monitor and promote the maturation of stem cell-derived cardiomyocytes. The $192,150 award to the New York Institute of Technology (NYIT) aims to create an integrated system that can non-invasively evaluate cardiomyocyte maturity in real-time and adaptively apply electrical and mechanical...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $517,390 Project Grant to the University of New Mexico (UNM) for the CAREER: Harnessing Multiscale Biophysical Cues for Engineering Adult Heart Tissue project. The goal of this 2-year research program, starting on October 1, 2025, is to develop a fundamental understanding of how multiscale biophysical signals can be used to improve the structural and functional maturity of engineered heart tissues. The project will...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $467,202 project grant to the Research Foundation of the City University of New York (RFCUNY) to develop an intelligent lab-on-chip device that can non-invasively monitor the maturation of stem cell-derived cardiomyocytes in real-time and apply adaptive biophysical stimulation to promote full cell maturation. The interdisciplinary research team from RFCUNY, City College of New York, and Rutgers University plans...
- This $1,000,000 National Science Foundation project grant will fund the Reproducible Cells and Organoids via Directed-Differentiation Encoding (RECODE) project at the University of Michigan from November 1, 2022 to October 31, 2026. The project aims to employ innovative biophysical, data-driven, and synthetic gene circuit engineering methods to better understand how adult human mesenchymal stem cells transform into chondrocytes, the cells that form cartilage. Specifically, the researchers will...
- This federal Project Grant award, funded by the National Science Foundation (NSF) Engineering program (CFDA 47.041), aims to engineer a biomaterial platform to investigate how the extracellular matrix (ECM) influences airway basal stem cell (BC) self-renewal and differentiation. The $350,000 award, with a period of performance from Nov 1, 2024 to Oct 31, 2027, will be executed by the University of Iowa. The research seeks to create a new material that simulates the composition and stiffness of...
- This National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant award of $600,000 to Dartmouth College aims to develop methodologies for efficiently manufacturing mature human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to accelerate drug development and cardiac disease modeling. The project will employ biochip design, machine learning, developmental biology, and tissue engineering approaches to enhance the structural and functional maturity of...
- This $500,000 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support the University of Notre Dame's research exploring the differentiation of stem cells into patterned blood vessel networks using hybrid memristor technology. Over a four-year period from October 2022 to September 2026, the University will engineer the first autonomous hybrid memory resistor and cell culture device to control human pluripotent stem cell differentiation into...
- This $125,805 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to develop new cell sorting technologies that can identify and separate cells based on changes in the activity of naturally occurring light-emitting molecules like NAD(P)H. The goal is to enable label-free, rapid identification and purification of cell populations, with a focus on stem cells and their functional subsets. The research will create a single cell deposition module to...
- This Project Grant award of $599,998.00 from the National Science Foundation's Engineering program (CFDA 47.041) supports the research project "CAREER: Topography-Mediated Immunomodulation for Implant-Associated Infections" at the University of Michigan. The project aims to address the significant challenge of implant-associated infections, which affect millions of patients and cost healthcare systems billions annually. The research explores how the physical properties of biomaterial...
This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) in the amount of $219,999 provides funding to the Regents of the University of Michigan to develop new approaches for precisely guiding stem cells to regenerate damaged tissues. The project, titled "CAREER: Engineering Instructive Niches to Precisely Guide Single Stem Cells," aims to create microenvironments that can direct fundamental stem cell processes like growth, division, and differentiation at the single-cell level. The research seeks to advance tissue engineering capabilities by providing engineered cell building blocks with locally defined properties. The educational component of the project will also engage high school teachers and students from diverse backgrounds in hands-on STEM research activities. This integrated research and educational effort is designed to promote multidisciplinary thinking and problem-solving critical for addressing complex challenges in biological systems. The project period is from December 15, 2025 to December 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $220.0k | 12/18/25 |