Project Grant 2542522
- The National Science Foundation Division of Environmental Biology awarded The Regents of the University of Colorado $309,862 on September 1, 2026, under the Biological Sciences program (CFDA 47.074) to develop artificial intelligence and machine-learning tools that predict how microbial communities in thawing permafrost soils change over time. The project combines new analytical methods for microbial DNA sequences with long-read DNA sequencing technology to create mathematical models forecasting...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded The Regents of the University of Colorado $1,058,870 on July 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the evolution of novel metabolic pathways from promiscuous enzyme activities. The research uses adaptive laboratory evolution coupled with genetic, omics, and biochemical approaches to understand how individual mutations assemble and optimize novel pathways and how...
- The National Science Foundation Division of Emerging Frontiers awarded The Regents of the University of Colorado $250,000 on July 1, 2026, under the Biological Sciences program (CFDA 47.074) to develop a standardized, AI-ready synthetic biology workflow that addresses the lack of machine-accessible experimental data and metadata across laboratories. The project will integrate standardized synthetic biology data workflows with advanced laboratory automation systems at the National Institute of...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded The Regents Of The University Of Colorado, doing business as University Of Colorado-Denver, $478,840 on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to conduct collaborative research on long-range signaling and computation in microtubules. The research tests the hypothesis that individual microtubule polymers function as transmitters and amplifiers of conformational signals within...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Colorado School of Mines $672,000 on June 1, 2026, under the Biological Sciences program (CFDA 47.074) to develop computational tools that combine physics-based simulations with machine learning to model biomolecular assembly pathways. The research addresses how and why certain assembly pathways are preferred over others in living systems that build complex structures by assembling small pieces in dynamic,...
- The Regents of the University of Colorado, doing business as the University of Colorado Denver, was awarded $333,918 under the National Science Foundation's Biological Sciences program (CFDA 47.074) to conduct collaborative research from July 1, 2023 to June 30, 2027. The university will use topological data analysis techniques to extract information embedded in plant leaf morphology and gene expression profiles, with the goal of predicting leaf shape from molecular data using deep learning...
- The National Institute of General Medical Sciences awarded Colorado State University $376,615 in funding on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop flexible Bayesian statistical methods for analyzing zero-inflated microbiome data and understanding microbial community dynamics and function. The project will produce a suite of scalable Bayesian methods designed to accommodate the high-dimensional, overdispersed, zero-inflated, and...
- The University of Colorado received a $111,471 Project Grant award from the National Science Foundation Division of Information and Intelligent Systems on September 1, 2021 to support research concluding on November 30, 2021. The grant funded collaborative research to accelerate synthetic biology discovery and exploration through knowledge integration under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). This program supports investigator-initiated...
- The National Science Foundation Division of Environmental Biology awarded a $343,925 Project Grant to The Regents of the University of Colorado to support research titled "COLLABORATIVE RESEARCH: PURSUIT: SPECIES DIVERSITY AND EVOLUTION OF PARASITIC MICROFUNGI." The three-year award, issued on August 15, 2021 with a projected completion date of July 31, 2024, will fund basic research under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote...
- The National Science Foundation awarded a $1.3 million Project Grant to the University of Colorado Denver under the Biological Sciences federal grant program (CFDA 47.074) for the period of July 15, 2021 through June 30, 2026. The grant funds research into protein degradation during the maternal-to-zygotic transition, as part of the NSF's mission to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and understanding of...
The National Science Foundation Division of Biological Infrastructure awarded The Regents of the University of Colorado (doing business as University of Colorado-Denver) $1,000,001 on September 1, 2026, under the Biological Sciences program (CFDA 47.074) to develop artificial intelligence and machine learning methods that detect genomic patterns linked to microbial niche adaptation across bacterial lineages including Staphylococcus, Pseudomonas, and Mycobacterium. The work addresses the microbial genotype-to-phenotype gap by applying protein language models and computational approaches to identify genes underlying niche adaptation—such as host switching, saltwater adaptation, and pathogen versus commensal adaptation—drawing on exponentially growing whole-genome sequencing datasets. The project includes development and release of detection tools and training for the next generation of computational biologists through R-Ladies+ community programs and a hands-on workshop series modeled on the Carpentries training framework. Performance runs from September 1, 2026, through August 31, 2031, at the University of Colorado-Denver campus in Aurora, Colorado. The Biological Sciences program supports basic research to advance scientific knowledge and strengthen the Nation's scientific enterprise.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 7/16/26 |