Project Grant 2541338
- Federal Grant Award Summary The National Science Foundation's Division of Emerging Frontiers awarded the University of Pittsburgh a $1.065 million Project Grant under the Biological Sciences program (CFDA 47.074) beginning June 1, 2026 and concluding May 31, 2030. This award supports research to develop integrated computational frameworks and imaging resources that bridge cryo-electron tomography (CryoET) and volume electron microscopy (VEM) technologies. The project will deliver standardized...
- Federal Project Grant Award Summary The University of North Carolina at Chapel Hill received a $1,039,048 CAREER award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) effective August 15, 2025, with a completion date of July 31, 2030. This project grant supports fundamental research investigating how animals allocate energy between maintaining their own cellular and organ systems versus investing in...
- Federal Project Grant Award Summary The University of Pittsburgh received a $470,000 Project Grant from the National Science Foundation's Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074) effective June 1, 2025, through May 31, 2028. The award supports BIORETS (Biological Research Education Translation), an integrated research-education program designed to train 18 high school and middle school science teachers in authentic microbiology research focused on...
- Federal Grant Award Summary Carnegie Mellon University received a $323,642 CAREER award from the National Science Foundation (NSF) Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2030. The award supports the development of novel mathematical and computational frameworks to understand how spatial heterogeneity in biological populations shapes evolutionary dynamics. Key deliverables include open-source...
- The University of Pittsburgh received a four-year, $855,989 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The grant will fund collaborative research between the University of Pittsburgh and other institutions to tackle functional protein states at atomic detail by integrating weighted ensemble simulations with magnetic resonance restraints. Over the period from July 2021 to June...
- The University of Pittsburgh was awarded a $650,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074) to study transcriptional regulation of CRB and MPP5 genes in nuclear space. Specifically, the award will fund research examining how differential transcription of genes related to cell polarization and patterning are spatially coordinated in the nuclei of zebrafish retinal cells. The...
- Federal Project Grant Award Summary The University of Massachusetts Lowell received an $880,000 Project Grant award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2026, through May 31, 2031. This CAREER award supports fundamental research investigating how transgenerational chromatin landscapes regulate gene expression and cell fate determination in Caenorhabditis elegans. The research...
- Federal Grant Award Summary The University of Pennsylvania received a $622,842 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences (CFDA 47.074) awarded on May 1, 2026, with completion targeted for April 30, 2030. This collaborative research project will generate fundamental scientific knowledge regarding zygotic genome activation (ZGA)—the critical biological transition in early embryonic development from reliance on maternal RNAs to...
- Grant Summary The University of Pittsburgh received a $649,684 Faculty Early Career Development (CAREER) Project Grant awarded May 1, 2026, through the National Science Foundation's Engineering program (CFDA 47.041), Division of Civil, Mechanical, and Manufacturing Innovation. The award supports a five-year research initiative (through April 30, 2031) establishing mathematical and computational foundations for bifurcation engineering—the systematic design of nonlinear dynamic systems that...
- Federal Project Grant Award Summary The University of Pittsburgh received a $1,066,082 Project Grant award from the National Science Foundation's Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074), effective August 15, 2025, through July 31, 2029. This award funds fundamental research to identify and characterize the ecological, molecular, genetic, and genomic mechanisms that enable beneficial bacteria to successfully colonize plant tissues and exclude...
Federal Project Grant Award Summary The University of Pittsburgh received a $1.253 million Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), awarded June 1, 2026, with a completion date of May 31, 2031. This CAREER award supports fundamental research investigating the principles and mechanisms underlying robust embryonic development. The project delivers three primary research products: (1) development and experimental validation of new mathematical theory explaining error-free cellular communication during embryogenesis, (2) creation and deployment of novel microscope technology enabling unprecedented observation and measurement of developmental errors, and (3) empirical research determining how embryos compensate for unexpected environmental changes. Beyond the research outputs, the project incorporates educational components designed to inspire the next generation of biologists by providing cutting-edge research experience to Pittsburgh-area high school students. The overarching objective is to discover new biological principles that enable bioengineers to construct replacement tissues with embryonic-level reliability and precision. The research focuses on the Nodal signaling pathway in zebrafish embryos to understand how embryos prevent, recognize, and correct developmental mistakes before they result in birth defects, thereby addressing fundamental gaps in understanding biological robustness in the face of environmental and genetic perturbations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 5/19/26 |