Project Grant 2536046
- Federal Project Grant Award Summary The University of Colorado-Denver received a $491,215 Project Grant from the National Science Foundation (NSF) Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), awarded August 15, 2026, with a completion date of July 31, 2029. The grant supports collaborative research to develop DeepSPIRAL, an innovative two-photon single-molecule localization microscopy technique designed to achieve super-resolution imaging at...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Biological Infrastructure awarded $360,000 to the University of Colorado on August 15, 2026, under the Biological Sciences program (CFDA 47.074) to develop DeepSpiral, an innovative two-photon super-resolution microscopy technique. This collaborative research project, scheduled for completion by July 31, 2029, will integrate multiphoton and single-molecule localization microscopies to enable cellular imaging at...
- Federal Project Grant Award Summary The University of Denver received a $948,390 Project Grant from the National Science Foundation's Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074) awarded November 1, 2025, with completion targeted for October 31, 2029. This collaborative research project will develop cell type-specific molecular tools for studying gene function in sponges, specifically the freshwater model organism Spongilla lacustris. The...
- This Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) provides $466,187 to the University of Portland (UP) to acquire a spinning-disk confocal microscope. The microscope will enable enhanced cell and molecular biology research and undergraduate teaching and training at UP and Lewis & Clark College. The award supports research programs investigating biological mechanisms such as developmental asymmetry, cardiac development, and the...
- The National Science Foundation awarded a $335,720 project grant to the University of Denver under the Biological Sciences federal grant program (CFDA 47.074) for work beginning August 1, 2021 through July 31, 2024. The grant will support research applying quantitative imaging methods to identify molecular components of multi-vesicular body fusion sites. The Biological Sciences program aims to advance biological knowledge and understanding of major problems through basic research, consistent...
- The National Science Foundation awarded $473,318 under the Engineering (47.041) federal grant program to the University of Denver from October 2022 through October 2026. The Project Grant funding will support research into developing multiplexed biomedical sensor systems for automated diagnosis using machine learning algorithms. Specifically, the university will investigate plexcimonic structures for ultrasensitive, simultaneous detection of multiple biomarkers. It will also develop algorithms...
- This $307,754 National Science Foundation Engineering Directorate project grant will fund the acquisition of a Nikon CSU-W1-SORA super-resolution spinning disk confocal microscope for Boston University. The microscope will enable new spatially resolved transcriptomics and multi-scale connectomics research techniques to study gene expression within cells and neural connectivity in brain networks. As a shared resource housed in BU's Photonics Center, the microscope is expected to serve nine...
- This $407,538 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research and development of a novel optical neuroimaging technology called Diffuse Correlation Spectroscopy (DCS) at Duke University. The goal is to enable deep tissue measurement of blood flow within the brain, which can provide valuable insights into neurological and mental health conditions. The project aims to develop a parallelized DCS system using single-photon...
- This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports the development of a new optical microscopy technology called "Space-Time-Pulsed Engineered-Excitation for Diffraction-Free Imaging (SPEEDI)." The technology utilizes exotic space-time wave packets to enable high-resolution fluorescence imaging of deep brain tissue without the light scrambling issues of conventional microscopy. The research aims to advance imaging...
- Federal Grant Award Summary The University of New Mexico received a $500,001 Project Grant award from the National Science Foundation's Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective August 1, 2025 through July 31, 2030. This CAREER award funds research and development of advanced optical microscopy systems utilizing pupil-matched remote focusing (PMRF) techniques to enable fast, high-resolution, label-free imaging of large biological...
The University of Denver received a $339,612 Project Grant from the National Science Foundation (NSF) Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), awarded August 15, 2026, with completion targeted for July 31, 2029. The award supports collaborative research to develop DeepSpiral, an innovative two-photon super-resolution imaging technique that combines multiphoton and single-molecule localization microscopies to enable cellular imaging at unprecedented depths within living tissue. This technological advancement addresses a critical limitation in current microscopy capabilities—the inability to visualize molecular structures and protein organization in deep brain tissue due to light scattering—thereby enabling researchers to study fundamental biological mechanisms of learning and memory at the cellular level. Beyond the primary neuroscience application, the project deliverables include computational modeling tools and methodologies applicable to diverse biological systems, engineering applications, and chemistry research. The award also funds an interdisciplinary training and education component, through which the research team will provide mentoring, training, and networking activities in fluorescence microscopy, neuroscience, and materials science to graduate and undergraduate students, with explicit connections to industrial career opportunities. The project team leverages an established track record in student mentorship and aims to strengthen workforce development in microscopy-based research across multiple scientific disciplines.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $339.6k | 7/13/26 |