Project Grant 2525681
Award Date
7/1/25
Completion Date
6/30/28
Dollars Obligated
$800K
Federal Agency
Division of Integrative Organismal Systems
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Olivette, MO 63132, USA
Similar Awards
This $451,139 Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program supports the development of a new biotechnology called Transposase-Assisted Homology-Independent Targeted Insertion (TAHITI) for intragenic genome engineering of plants. The research aims to improve crop traits like disease resistance and yield by precisely inserting DNA sequences sourced from the same plant species, rather than relying on transgenic approaches that introduce...
This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
This $699,870 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports the development of simplified and highly efficient genetic modification technologies for economically important grasses and cereal crops. The "PLANTTRANSFORM: SMART GRASS" project aims to overcome the current constraint in the plant science research community regarding the capacity to genetically modify major crop plants. The award establishes a...
This federal Project Grant award of $1,192,499.00 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research by the Donald Danforth Plant Science Center in Missouri to develop epigenetic editing tools for crop improvement. The key objectives of this 4-year project are to: 1) Expand epigenetic editing technologies to other crop species beyond cassava, such as rice and tomato, to enable disease resistance; 2) Demonstrate additional applications of...
This $998,790 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support enhancing global plant transformation capacity through research, training, and partnerships led by Boyce Thompson Institute For Plant Research Inc. Over a three-year period, the grantee will establish a global research coordination network to collectively address challenges to plant genetic engineering and gene editing efficiency. The network aims to facilitate collaboration,...
This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
This Project Grant award of $750,000 from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports collaborative research between U.S. and Swiss investigators to develop a high-throughput platform for identifying transcription factor binding sites during plant lateral organ development. The goal is to create a semi-automated system to determine which genes are active in different plant organ types, such as roots, leaves, and flowers, across two divergent plant...
This Project Grant award from the National Science Foundation's Biological Sciences Federal Grant Program (CFDA 47.074) provides $279,000 to fund a postdoctoral research fellowship at Purdue University. The fellowship, titled "Determinants of Evolutionary Success for Active Transposable Element Populations in the Maize Genomic Ecosystem," will support research and training to investigate the dynamics of transposable elements in corn plants. The research aims to characterize how the...
This $959,997 federal Project Grant, awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074), supports collaborative research at the Cold Spring Harbor Laboratory to develop improved methods for plant transformation and regeneration. The research aims to provide a thorough understanding of the molecular mechanisms underlying regeneration in maize, a key crop that provides a substantial portion of human caloric intake. By exploiting a "morphogenic-based"...