Project Grant 2521342
- This $999,470 federal Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) will support a collaborative research effort to develop methods for discovering and designing small molecules that can combat antibiotic resistance, biofilms, and aflatoxin contamination. The lead institution, South Dakota State University (SDSU), will partner with South Dakota Mines (SDM) and the University of Nevada, Las Vegas (UNLV) to leverage artificial...
- This $809,743 Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) will develop an artificial intelligence (AI) and machine learning (ML)-driven platform to accelerate the discovery and optimization of small molecules for combating antibiotic resistance, biofilms, and aflatoxin contamination. The collaborative effort between South Dakota State University (lead), South Dakota Mines, and the University of Nevada, Las Vegas will pursue three...
- This Project Grant award of $687,304 from the National Science Foundation's Biological Sciences (CFDA 47.074) program will enable the South Dakota School of Mines and Technology to acquire a BioLector XTM microbioreactor system. This specialized equipment can simultaneously grow and monitor up to 48 microbial cultures, replicating large-scale industrial fermentation conditions at a small scale. It will facilitate advanced research across disciplines such as microbiology, biochemical engineering,...
- This National Science Foundation (NSF) Research Traineeship (NRT) award to the South Dakota School of Mines and Technology (SDSM&T), in collaboration with the University of South Dakota, Black Hills State University, and Oglala Lakota College, will train 70 students, including 26 funded trainees, across master's and doctoral programs in data science, biosciences, and engineering. The $3,000,000 grant, awarded under the NSF's STEM Education program (CFDA 47.076), will prepare students to...
- This $199,280 federal Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) will fund a workshop for artificial intelligence (AI)-powered materials discovery at the University of South Dakota (USD). The goal is to unite researchers from nine EPSCoR jurisdictions with experts in AI, engineering, materials science, physical science, and data science to create a world-class, data-driven materials research platform. The workshop will leverage...
- This NSF Integrative Activities (CFDA 47.083) Project Grant award of $299,797 to South Dakota State University (SDSU) aims to investigate the feasibility of using dental biofilms and sulfate-reducing bacteria (SRB) to enhance the strength of soils, thereby mitigating soil erosion and scouring, and improving agricultural productivity and the resilience of civil infrastructure. The key products and services to be delivered under this 2-year award include conducting a series of strength-based and...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) was granted to South Dakota State University in the amount of $229,589 to be performed from January 1, 2025 to December 31, 2027. The primary objectives of this research project are to: 1) use machine learning to identify critical factors in the transformation of phenols to aliphatic disinfection byproducts (DBPs) in drinking water, 2) investigate the formation of aliphatic DBPs and halophenols...
- This $220,000 Project Grant award from the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE) program supports the development of advanced computational methodologies for drug discovery and development. The primary awardee, the Regents of the University of Minnesota, will create a comprehensive generative AI framework capable of efficiently generating high-quality drug candidates with multiple desired properties. This initiative aims to expedite...
- This federal Project Grant award, valued at $596,920 and provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041), aims to develop a mechanism-informed AI platform to optimize biomanufacturing processes for life-saving biopharmaceuticals. Led by Northeastern University, the project will leverage emerging sensing technologies to efficiently decode the fundamental mechanisms underlying complex biomanufacturing systems. The goal is to create a flexible and robust AI-based...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) provides $272,799 to South Dakota State University to conduct collaborative research on the development and mechanistic studies of microenvironment-sensitive polymeric nanoparticles. The objective is to create nanometer-scale polymeric particles that can deliver therapeutics to target areas while also enhancing ultrasound imaging capabilities. The research team...
This Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) will provide $2,190,786 to South Dakota State University (SDSU) to develop methods for discovering and designing small molecules to combat antibiotic resistance, microbial biofilms, and aflatoxin contamination. The 4-year project will leverage artificial intelligence (AI) and machine learning (ML) tools to accelerate the identification of bioactive compounds across three focus areas: 1) inducing bacterial cell death, 2) inhibiting biofilm maintenance proteins, and 3) neutralizing fungal toxins. The collaborative effort will also enhance research infrastructure, develop teaching modules and lab kits for K-12 and undergraduate instruction, and expand biofilm and aflatoxin assay capabilities across SDSU, South Dakota Mines, and the University of Nevada, Las Vegas. This use-inspired project aims to advance human and animal health, prevent microbial infrastructure deterioration, and improve food safety.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.2m | 8/7/25 |