This Project Grant award for $344,139 from the National Science Foundation (NSF) Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research to develop and study polymer nanoparticles (polymersomes) with the dual capability of delivering therapeutics and enabling ultrasound imaging. The research team from George Washington University aims to synthesize nanoscale polymeric particles that can evade the body's defense system,...
This National Science Foundation Project Grant of $676,969 supports research at North Dakota State University from May 1, 2023 to April 30, 2028 under the Engineering program (CFDA 47.041). The grant aims to advance fundamental understanding of enzyme interactions with stimuli-responsive nanoparticles at the nanoscale. Specifically, the Principal Investigator will develop histone-mimetic polymerosomes capable of selectively recognizing target enzymes like histone deacetylase, and study how their...
This $249,118 National Science Foundation Mathematical and Physical Sciences project grant funds the development of stimuli-responsive, biocompatible and biodegradable polymeric nanomaterials for biomedical applications at the University of North Dakota from July 15, 2022 to June 30, 2024. Professor Binglin Sui and students will create a series of degradable polymer chains containing bio-cleavable bonds. The polymers and polymer-based nanosystems are designed to covalently conjugate...
This Project Grant award of $424,389.00 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of a novel thermogel design using polymeric nanoparticles with "patchy" thermosensitive domains. The goal is to establish a modular approach for creating thermogels with enhanced control over properties like mechanical behavior, degradability, and biological functionality. The research aims to enable the development of...
This $311,242 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research to elucidate the nanoscale interactions between invertible micellar assemblies and biopolymer cargos under varied environmental conditions. The research team from the University of Missouri System aims to understand how the properties of cargo-loaded invertible micellar assemblies impact their efficiency in drug delivery, and the significance of their unique...
This $500,000 Project Grant from the National Science Foundation Division of Materials Research supports the development of antibody-mimicking polymeric nanoparticles for site-specific protein labeling and protein-binding applications. Funded under the Mathematical and Physical Sciences program (CFDA 47.049), Professor Yan Zhao at Iowa State University will pursue two aims - site-specific labeling of proteins with single or multiple tags using the nanoparticles, and developing nanoparticle...
The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $575,725 to the South Dakota School of Mines & Technology through its Engineering (CFDA 47.041) federal grant program. This five-year Project Grant, beginning February 1, 2022 through January 31, 2027, will support research determining and tuning the impact of low-level metal-based nanoparticles on actin cytoskeleton in normal and cancer cells. The South Dakota School of Mines...
This $688,144 Project Grant was awarded on May 1, 2025 by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049). The grant supports researchers at the University of Utah, Professors Ilya Zharov and John Conboy, along with their students, in investigating the molecular-level interactions between polymer-grafted silica nanoparticles during self-assembly. Using sum-frequency generation (SFG) vibrational...
The National Science Foundation (NSF) awarded a $124,564 Project Grant under the Integrative Activities program (CFDA 47.083) to the University of South Dakota (USD) to develop water-soluble afterglow luminescent nanocomposites for bioimaging and bioanalysis. This 2-year project, co-funded by the NSF Directorates for Mathematical and Physical Sciences (MPS) and the Established Program to Stimulate Competitive Research (EPSCoR), aims to synthesize and characterize novel carbon dot-doped...
This $132,962 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (MPS) program supports research at the University of Miami to engineer polymeric nanoparticles that can selectively sequester inflammatory cytokines. The goal is to develop a novel nanomedicine approach to treat various diseases by removing these cytokines without the side effects associated with traditional drug-based therapies. The key technical objectives are to: 1) use sulfated...