Project Grant 2518022
- This $325,937 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports collaborative research at Michigan State University (MSU) to interrogate the interconnection of structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments. The project aims to study the impact of geometry and permeability of microcompartments in two distantly related bacteria under varying realistic environments, with the goal of gaining...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) federal project grant provides $347,628 to Purdue University from June 1, 2025 to May 31, 2030 to research the assembly and supramolecular organization of bacterial microcompartments. The project combines cryo-electron tomography, mathematical modeling, and biochemical assays to develop a model of how these large protein assemblies are built, mature, and function. The research aims to advance understanding of how beneficial...
- This federal Project Grant award of $339,999, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research to study the spatiotemporal dynamics of intercellular signaling in engineered multicellular bacterial systems. The research aims to develop novel mathematical modeling techniques that can better predict the behavior of spatially extended synthetic bacterial populations, which have potential applications...
- This National Science Foundation (NSF) Project Grant under the Biological Sciences program (CFDA 47.074) was awarded to Bigelow Laboratory for Ocean Sciences for $396,577 to conduct research on the evolutionary patterns, systematics, and biogeographic distribution of two abundant but understudied groups of bacteria known as Patescibacteria and Chloroflexota. The research aims to improve fundamental knowledge about these cryptic microbes that play important roles in marine sediment ecosystems and...
- This $160,000 federal Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research on the spatiotemporal dynamics of intercellular signaling in growing bacterial populations. The research aims to develop mathematical modeling techniques to better understand and predict the behavior of engineered multicellular bacterial systems, which have potential applications in areas like gut microbiome...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) federal Project Grant award provides $501,879.00 to the University of Chicago to conduct collaborative research on the structural and functional mechanisms of a molecular conveyor belt machinery that drives bacterial gliding motility. The project aims to determine how multiple rotary motors on the bacterial surface coordinate to propel a protein-based conveyor belt, enabling cell movement analogous to a molecular...
- This two-year National Science Foundation Project Grant of $199,998 provides funding for modeling bacterial microcompartment assembly using a multiscale computational framework. The grant is awarded under the NSF Engineering program (CFDA 47.041) to the Colorado School of Mines to investigate the Haliangium ochraceum microcompartment. Researchers will quantify protein oligomerization free energy landscapes and classify molecular determinants controlling microcompartment morphology using...
- This $650,001 federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research by the University of Chicago on the periplasmic biomineralization of semiconductors and semiconductor alloys for living photosensitive biomaterials. The goal is to establish a robust protocol for incorporating light-harvesting semiconductor nanoclusters into the periplasmic space of bacteria, which can enhance the efficiency of chemical...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 will fund a 3-year postdoctoral fellowship to research the adaptive response of bacteria to bacteriophage infection and high hydrostatic pressure. The fellow will develop novel fluorescence microscopy techniques to quantify bacterial growth, cell size, and morphology under these environmental stressors using model organisms E. coli, P. aeruginosa, and S. piezotolerans. The project...
- This Project Grant award of $876,272.00 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will fund collaborative research to develop advanced genetic manipulation tools for bacteria. The project aims to expand the biotechnological capabilities of marine bacteria called Vibrios, which are important in food production, disease, and host-microbe interactions. The research will focus on scaling up methods to influence the expression of individual bacterial genes...
This Project Grant award, totaling $30,000.00, was provided by the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program to Northwestern University. The award will support collaborative research to investigate the structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments from September 1, 2025 to August 31, 2028. The research aims to provide a generalizable understanding of how bacterial microcompartments, which allow certain bacteria to grow and process molecules, are built and regulated. This knowledge can inform new strategies for bioengineering chemical production and controlling bacterial pathogens. The project will also involve educational and training outreach programs, including the integration of undergraduate researchers and the development of a new case study for undergraduate courses on protein engineering. Additionally, the team will analyze the potential of synthetic biology to support new manufacturing strategies as part of the growing bioeconomy.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $30.0k | 8/18/25 |