Project Grant 2451529
- This federal Project Grant award of $339,999, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research to study the spatiotemporal dynamics of intercellular signaling in engineered multicellular bacterial systems. The research aims to develop novel mathematical modeling techniques that can better predict the behavior of spatially extended synthetic bacterial populations, which have potential applications...
- This federal Project Grant award of $100,000 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) will support collaborative research to better understand bacterial locomotion through complex biological fluids like mucus. The research will combine mathematical modeling, computer simulations, and laboratory experiments to investigate how bacteria, using their flagella, propel themselves through viscoelastic fluids. The project aims to develop a...
- This Project Grant award for $150,000.00, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports fundamental research on the multiscale dynamics of bacterial flagella movement through complex biological fluids like mucus. The research combines mathematical modeling, computer simulations, and laboratory experiments to investigate how bacteria swim through viscoelastic fluids, which is crucial for understanding infections in...
- This federal Project Grant award of $1,000,000.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) was provided to The Trustees of Princeton University to study "Quorum Sensing Across Scales and Between Domains". The project aims to investigate bacterial communication processes, known as quorum sensing, to better understand how bacteria can synchronize behavior and potentially control harmful pathogens or promote beneficial bacteria. Key objectives...
- This federal Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences program (CFDA 47.049) in the amount of $285,773 will support an experimental study on the microscopic dynamics of bacterial turbulence. The research aims to uncover the mechanisms underlying the collective swimming of bacteria in dense suspensions, which exhibit emergent collective behaviors analogous to phenomena seen in active matter systems like schooling fish and flocking birds. The...
- This $309,797 Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) will support a two-pronged research effort to study the emergence of long-range coherence in motile microorganismal systems with quenched disorder. The first component involves experimental studies of bacteria, amoeba, and bladder cancer cells in disordered environments to understand how self-propelled motion leads to large-scale collective behavior. The...
- The National Science Foundation (NSF) awarded a $100,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to The Regents of the University of Colorado (CU) for the project "COLLABORATIVE RESEARCH: EMB: MULTISCALE FLAGELLAR DYNAMICS IN COMPLEX BIOLOGICAL FLUIDS." This 3-year research project aims to develop mathematical models and simulations to study how bacteria swim through complex biological fluids like mucus, which play a crucial role in health and...
- This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports a collaborative research project focused on understanding the mechanics and morphogenesis of bacterial biofilms. The award, with an effective date of December 1, 2025 and a completion date of November 30, 2028, will enable researchers at Yale University to conduct detailed observations and theoretical modeling of biofilm growth under varying environmental conditions, such as...
- The National Science Foundation (NSF) awarded a $166,667 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Texas Health Science Center at Houston (UTHealth). This 3-year grant, effective May 1, 2024, supports interdisciplinary research to decipher the composition, architecture, and mechanism of the gliding motility machinery in bacteria. The project employs cutting-edge techniques like cryogenic electron microscopy and fluorescence microscopy...
- This $300,000 project grant, awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), is focused on collaborative research to deepen the understanding of biofilm development and growth in constrained environments. The project aims to leverage highly tunable bacterial biofilm systems as a model to study the mechanics and morphogenesis of biological growth processes. Through a combination of confocal imaging, data analysis, and theoretical modeling, the...
This $160,000 federal Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research on the spatiotemporal dynamics of intercellular signaling in growing bacterial populations. The research aims to develop mathematical modeling techniques to better understand and predict the behavior of engineered multicellular bacterial systems, which have potential applications in areas like gut microbiome maintenance, cancer therapy, and engineered living materials. The award recipient is the University of Houston System, which will leverage its expertise in synthetic biology, mathematical modeling, and undergraduate/graduate student training to carry out this research project over a 3-year period from September 2025 to August 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $160.0k | 8/5/25 |