Project Grant 2525727
- This federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support the development of advanced tools for genetic manipulation of bacteria, with a focus on marine Vibrio bacteria. The $427,981 award, effective October 15, 2025 through September 30, 2028, will fund the creation of new CRISPR-based techniques to precisely control gene expression in bacteria, enabling a wide range of biotechnology applications. The project will test these...
- This Project Grant award, totaling $479,999.00, was provided by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program to The Johns Hopkins University. The project, titled "CAREER: Exploring Novel Interactions between CRISPR-Cas Systems and Temperate Bacteriophages", will investigate how CRISPR-Cas immunity systems, a powerful gene editing technology, interact with temperate bacteriophages (viruses that infect bacteria). The research aims to enhance...
- This Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) will fund research to characterize the function of an unknown protein found in many bacteria, including pathogenic strains. The $300,000 award, effective from February 15, 2025 to January 31, 2028, will investigate how this protein influences the synthesis of bacterial pili, which are structures used for attachment and biofilm formation. The project aims to provide a foundation...
- The National Science Foundation (NSF), under its Biological Sciences program (CFDA 47.074), awarded the University of Wisconsin System $621,502 on August 15, 2023 for a project titled "COLLABORATIVE RESEARCH: EDGE FGT: DEVELOPMENT OF A COMPREHENSIVE SELECTION LIBRARY TO RECONCILE CORE METABOLIC KNOWLEDGE GAPS". The project aims to develop tools and resources (algorithms, strains, and plasmids) to rapidly identify the functions of genes in non-model organisms, in order to better...
- This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
- The National Science Foundation Division of Integrative Organismal Systems awarded $550,000 to the Massachusetts Institute of Technology under the Biological Sciences (CFDA 47.074) federal grant program to support the project "EDGE FGT: Genetic Tools for Prochlorococcus That Dominate the Oceans" from May 1, 2021 to April 30, 2023. The project aims to develop genetic tools to study Prochlorococcus, a genus of photosynthetic bacteria that are abundant in oceans worldwide. A sub-award...
- This three-year, $409,923 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of genomic algorithms and statistical models to study natural gene transfer in transformable bacteria at the University of Wisconsin-Madison. The university will collaborate with partners to generate genome-scale statistical algorithms and computational tools for analyzing molecular and biological drivers of gene transfer events during natural...
- This $1,000,000 Project Grant was awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program to The Trustees of Princeton University on August 1, 2025. The grant will fund a 4-year research project to study "quorum sensing" - the process by which bacteria communicate and coordinate their behaviors on a population-wide scale. The project aims to expand knowledge of how quorum sensing controls interactions between bacteria and bacteriophages...
- This $396,577 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports fundamental research on the evolutionary patterns, functional roles, and biotechnology potential of two abundant yet understudied lineages of bacteria: Patescibacteria and Chloroflexota. The research aims to enhance understanding of these "microbial dark matter" lineages that thrive in marine sediments, a key component of ocean ecosystems. The project will...
- This $300,000.00 federal Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports collaborative research on the mechanics and morphogenesis of bacterial biofilms. The research aims to deepen the understanding of biofilm development in constrained environments and leverage biofilms as a model system for studying biological growth processes. The project, awarded to Yale University, will involve confocal imaging and analysis to observe growth...
This Project Grant award, titled "COLLABORATIVE RESEARCH: EDGE FGT: ADVANCING CRISPR APPROACHES FOR BACTERIAL FUNCTIONAL GENOMICS APPLIED TO MARINE VIBRIO-HOST INTERACTIONS," was provided by the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program for $876,272.00 beginning on October 15, 2025. The project aims to develop tools to enable genetic manipulation of bacteria, specifically marine Vibrio bacteria, to facilitate a range of biotechnology applications. The key products to be delivered include laboratory protocols, teaching materials, computer code, DNA sequence databases, and bacterial strains that will enable broader adoption and application of the new CRISPR-based technology for bacterial functional genomics. This will expand the biotechnological reach of available bacteria and provide important resources for research and educational use. The University of Wisconsin System, a leading public research institution, is the primary awardee for this 3-year project set to conclude on September 30, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $876.3k | 7/24/25 |