Project Grant 2517858
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $275,989 Project Grant to William Marsh Rice University in Houston, TX. The grant, with a project period from March 1, 2025 to February 28, 2030, aims to develop advanced tools to visualize, quantify, and correlate DNA dynamics, organization, and gene activity in human cells with unprecedented resolution. The project will apply innovative labeling strategies, 3D nanoscale imaging, and...
- This $754,903 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program will fund research at Yale University from March 1, 2025 to February 29, 2028. The project aims to provide a better understanding of how the structure and organization of the endoplasmic reticulum (ER) in cells influences the functioning of the peptide loading complex, which plays a critical role in immune recognition. Specifically, the research will examine the...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Rice University a $373,174 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to advance biological knowledge and understanding of major problems to strengthen the nation's scientific enterprise....
- This $500,000 Project Grant was awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) to William Marsh Rice University in Houston, Texas. The funding will support research to increase the secretion capacity of therapeutic cells, enabling them to produce higher levels of proteins to aid in disease treatment. The project aims to understand the mechanisms driving high antibody production in plasma cells and apply these insights to modify existing therapy-grade cells....
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded William Marsh Rice University a $1,191,793 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period of January 1, 2022 through December 31, 2025. The grant funds research into the signaling logic underlying mammalian germ layer differentiation. Specifically, Rice University researchers will work to increase scientific understanding of the major biological processes...
- This $414,159 Project Grant, awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the differential stress responses of organelles in eukaryotic cells. The research aims to investigate the molecular mechanisms underlying how cells employ different strategies to respond to nutritional deprivation versus endoplasmic reticulum (ER) stress. The principal investigator at the...
- The National Science Foundation (NSF) awarded a $623,295 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to William Marsh Rice University in Houston, TX. The purpose of this 3-year grant, with an award date of August 1, 2025, is to develop new methods for isolating, studying, and utilizing a wider variety of DNA plasmids as tools to program microbes for beneficial purposes. The research aims to expand the current limited plasmid toolbox from a few to potentially...
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to the University of Kansas Center for Research Inc. in the amount of $464,355. The grant will support an REU (Research Experiences for Undergraduates) site program titled "The Stressed Life of Cells" from June 1, 2025 to May 31, 2028. The program will train 10 undergraduate students per summer for 10 weeks, providing hands-on research experiences in...
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences (CFDA 47.074) program to The Johns Hopkins University totaling $856,135. The award will fund research to develop and apply new single-molecule methods to measure protein production in individual live cells, rather than population averages. The goal is to better understand the regulatory mechanisms governing when and where protein production occurs in cells. In addition to the core research, the project...
- This federal Project Grant award of $339,999, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research to study the spatiotemporal dynamics of intercellular signaling in engineered multicellular bacterial systems. The research aims to develop novel mathematical modeling techniques that can better predict the behavior of spatially extended synthetic bacterial populations, which have potential applications...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) in the amount of $828,803 aims to better understand how cells determine their fate when under stress in the endoplasmic reticulum (ER), the cell's power plant that produces and folds proteins. The research project at William Marsh Rice University develops new tools to investigate how genes behave in real-time and create systems to help cells better manage protein production under stress. The results could lead to new ways to engineer healthier, more resilient cells. The project also provides educational and training opportunities for graduate, undergraduate, and high school students in this highly multidisciplinary research environment. The award period runs from August 15, 2025 through July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $828.8k | 7/22/25 |